HitPredict

Interactor 1: UCHL1 (P09936)
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1) (EC 3.4.19.12) (Neuron cytoplasmic protein 9.5) (PGP 9.5) (PGP9.5) (Ubiquitin thioesterase L1)
Gene: UCHL1

Interactor 2: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	18550537, 18635949
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 223 Hs			1 646
+	Hs
		503371 UCHL3_HUMAN (2-222): 2.74e-100: 292: 54.43		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		504488 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		714033 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		HS71L_HUMAN (2-646): 0: 966: 82.48
+	Hs
		564140 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		HSP76_HUMAN (6-646): 0: 955: 77.54
+	Hs
		871707 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		HSP72_HUMAN (2-646): 0: 940: 85.47
+	Dm
		505068 CALYP_DROME (3-220): 1.47e-76: 239: 22.69		HSP7D_DROME (1-612): 0: 938: 86.60