Interactor 1: CLPP (P0A6G7)
ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) (Caseinolytic protease) (Endopeptidase Clp) (Heat shock protein F21.5) (Protease Ti)
Gene: CLPP

Interactor 2: CLPA (P0ABH9)
ATP-dependent Clp protease ATP-binding subunit ClpA
Gene: CLPA

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.902

The method score is based on:

Property Details
Experiments 19368884, 20462489, 15690043, 1783205
Identification Methods light scattering, enzymatic study, electron microscopy, molecular sieving, classical fluorescence spectroscopy, 3D electron microscopy, tandem affinity purification, pull down
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_2~CLP_protease
Common GO terms GO:0004176 - ATP-dependent peptidase activity
GO:0005829 - cytosol
GO:0006515 - protein quality control for misfolded or incompletely synthesized proteins
GO:0009368 - endopeptidase Clp complex
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 207
Ec

1 758
+ Bs
+ At
+ At
+ Mt

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Last updated: 15 Jul 2024