HitPredict

Interactor 1: EFTS (P0A6P1)
Elongation factor Ts (EF-Ts) (Bacteriophage Q beta RNA-directed RNA polymerase subunit IV)
Gene: tsf

Interactor 2: EFTU1 (P0CE47)
Elongation factor Tu 1 (EF-Tu 1) (Bacteriophage Q beta RNA-directed RNA polymerase subunit III) (P-43)
Gene: tufA

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	1.00	0.901

Property	Details
Experiments	16606699, 20798060, 15690043, 16858726
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification, blue native page
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	EF_TS~GTP_EFTU, EF_TS~GTP_EFTU_D3
Common GO terms	GO:0003746 - translation elongation factor activity GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006414 - translational elongation GO:0032045 - guanyl-nucleotide exchange factor complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 283 Ec			1 394
+	Ec
		458601 EFTS_ECOLI (1-283): 5.78e-109: 318: 100.00		EFTU2_ECOLI (1-394): 9.26e-158: 451: 99.75
+	Mp
		618374 EFTS_MYCPN (7-282): 1.4e-88: 267: 38.91		EFTU_MYCPN (1-393): 2.95e-155: 444: 70.23
+	Bt
		799171 EFTS_BOVIN (6-271): 3.65e-93: 280: 24.32		EFTU_BOVIN (2-391): 5.69e-149: 431: 56.12
+	Bs
		702822 EFTS_BACSU (3-282): 1.86e-90: 272: 48.97		EFTU_BACSU (1-392): 1.24e-152: 438: 76.65
+	Hs
		799178 EFTS_HUMAN (2-259): 2.89e-89: 270: 24.65		EFTU_HUMAN (2-394): 4.36e-147: 426: 55.44
+	Dm
		1179843 EFTS_DROME (4-268): 8.27e-86: 260: 27.65		Q7K3V6_DROME (8-393): 7.71e-134: 392: 51.03
+	Ce
		105315 EFTS_CAEEL (3-262): 4.85e-68: 215: 23.76		G5ECM6_CAEEL (3-393): 5.03e-131: 386: 51.13
+	Ce
		106058 EFTS_CAEEL (3-262): 4.85e-68: 215: 23.76		G5EDF5_CAEEL (10-392): 2.57e-111: 334: 45.46