HitPredict

Interactor 1: DNAK (P0A6Y8)
Chaperone protein DnaK (HSP70) (Heat shock 70 kDa protein) (Heat shock protein 70)
Gene: DNAK

Interactor 2: DCEA (P69908)
Glutamate decarboxylase alpha (GAD-alpha) (EC 4.1.1.15)
Gene: gadA

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.612

Property	Details
Experiments	16606699, 15690043
Identification Methods	affinity chromatography technology, tandem affinity purification, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 638 Ec			1 466
+	Ec
		459300 DNAK_ECOLI (1-638): 0: 871: 100.00		DCEB_ECOLI (1-466): 7.25e-173: 495: 98.93
+	Hs
		504279 HSP7C_HUMAN (2-604): 0: 844: 48.22		GADL1_HUMAN (5-448): 1.52e-130: 389: 12.47
+	Hs
		871630 HSP72_HUMAN (2-604): 0: 833: 47.67		GADL1_HUMAN (5-448): 1.52e-130: 389: 12.47
+	Dm
		947901 HSP70_DROME (3-624): 0: 820: 47.64		Q9VPH6_DROME (39-448): 3.34e-116: 352: 13.21
+	Dm
		115691 HSP72_DROME (3-623): 0: 821: 48.19		M9PG67_DROME (131-448): 1.8e-90: 280: 12.68
+	Sc
		478526 HSP77_YEAST (2-600): 0: 653: 59.50		SGPL_YEAST (3-459): 2.06e-108: 334: 17.27
+	Sc
		766213 HSP7E_YEAST (4-572): 0: 625: 58.70		SGPL_YEAST (3-459): 2.06e-108: 334: 17.27
+	Sc
		477939 HSP77_YEAST (2-600): 0: 653: 59.50		NFS1_YEAST (77-460): 1.61e-29: 122: 14.93