Interactor 1: RPOA (P0A7Z4)
DNA-directed RNA polymerase subunit alpha (RNAP subunit alpha) (EC 2.7.7.6) (RNA polymerase subunit alpha) (Transcriptase subunit alpha)
Gene: RPOA

Interactor 2: NUSA (P0AFF6)
Transcription termination/antitermination protein NusA (N utilization substance protein A) (Transcription termination/antitermination L factor)
Gene: NUSA

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 0.90 0.765

The method score is based on:

Property Details
Experiments 21742261, 15690043
Identification Methods nuclear magnetic resonance, tandem affinity purification, pull down
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains HHH_5~RNA_pol_A_CTD, NusA_N~RNA_pol_A_CTD
Common GO terms GO:0005829 - cytosol
GO:0008023 - transcription elongation factor complex
GO:0031564 - transcription antitermination
GO:0032784 - regulation of DNA-templated transcription elongation
Homologous interactions 0

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Last updated: 15 Jul 2024