Protein: SAS10
Something about silencing protein 10 (Charged amino acid-rich leucine zipper 1) (CRL1) (Disrupter of silencing SAS10) (UTP3 homolog)

Gene: SAS10, UTP3
Organism: Homo sapiens
Interactions: 149
UniProt ID: Q9NQZ2

Gene Ontology (top 5):
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

586907

RS2
Small ribosomal subunit protein uS5

3

2

High-throughput

0.667

High

644082

FBRL
rRNA 2'-O-methyltransferase fibrillarin

4

0

High-throughput

0.657

High

979275

RS6
Small ribosomal subunit protein eS6

3

2

High-throughput

0.656

High

1228333

UTP25
U3 small nucleolar RNA-associated protein 25 homolog

3

1

High-throughput

0.656

High

397016

ESR1
Estrogen receptor

3

4

High-throughput

0.640

High

1446193

EXOS4
Exosome complex component RRP41

2

2

High-throughput

0.628

High

1447636

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

2

3

High-throughput

0.628

High

521963

H14
Histone H1.4

2

6

High-throughput

0.621

High

1037394

H11
Histone H1.1

2

6

High-throughput

0.621

High

985014

RL31
Large ribosomal subunit protein eL31

2

2

High-throughput

0.611

High

1447638

NOP53
Ribosome biogenesis protein NOP53

2

0

High-throughput

0.602

High

447485

NPM
Nucleophosmin

2

2

High-throughput

0.601

High

595608

H15
Histone H1.5

2

6

High-throughput

0.601

High

596377

H12
Histone H1.2

2

6

High-throughput

0.601

High

1418604

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

2

0

High-throughput

0.585

High

373238

MYC
Myc proto-oncogene protein

2

3

High-throughput

0.584

High

1447305

ANLN
Anillin

2

1

High-throughput

0.584

High

1336599

FSAF1
40S small subunit processome assembly factor 1

2

0

High-throughput

0.580

High

1392130

CDA7L
Cell division cycle-associated 7-like protein

1

0

High-throughput

0.549

High

140635

MPP10
U3 small nucleolar ribonucleoprotein protein MPP10

1

3

High-throughput

0.536

High

287154

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

6

High-throughput

0.536

High

301227

RL1D1
Ribosomal L1 domain-containing protein 1

1

1

High-throughput

0.536

High

419223

H2A1B
Histone H2A type 1-B/E

1

1

High-throughput

0.536

High

429008

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.536

High

476841

RSSA
Small ribosomal subunit protein uS2

1

4

High-throughput

0.536

High

616005

RL17
Large ribosomal subunit protein uL22

1

1

High-throughput

0.536

High

650582

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

1

2

High-throughput

0.536

High

686463

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.536

High

783668

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

1

High-throughput

0.536

High

809864

RS19
Small ribosomal subunit protein eS19

1

3

High-throughput

0.536

High

860969

RS10
Small ribosomal subunit protein eS10

1

2

High-throughput

0.536

High

969469

RS8
Small ribosomal subunit protein eS8

1

2

High-throughput

0.536

High

975971

RL7A
Large ribosomal subunit protein eL8

1

1

High-throughput

0.536

High

978746

RL23A
Large ribosomal subunit protein uL23

1

1

High-throughput

0.536

High

985908

RL11
Large ribosomal subunit protein uL5

1

1

High-throughput

0.536

High

1008901

RED1
Double-stranded RNA-specific editase 1

1

3

High-throughput

0.536

High

1061171

SRSF1
Serine/arginine-rich splicing factor 1

1

3

High-throughput

0.536

High

1099563

SRSF6
Serine/arginine-rich splicing factor 6

1

5

High-throughput

0.536

High

1112192

KRR1
KRR1 small subunit processome component homolog

1

2

High-throughput

0.536

High

1151209

OASL
2'-5'-oligoadenylate synthase-like protein

1

1

High-throughput

0.536

High

1194400

LARP7
La-related protein 7

1

1

High-throughput

0.536

High

1252687

ZN574
Zinc finger protein 574

1

1

High-throughput

0.536

High

1260439

H1FNT
Testis-specific H1 histone

1

1

High-throughput

0.536

High

1275700

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

1

High-throughput

0.536

High

1361771

DGCR8
Microprocessor complex subunit DGCR8

1

1

High-throughput

0.536

High

1370545

FGF13
Fibroblast growth factor 13

1

2

High-throughput

0.536

High

1390626

NEIL1
Endonuclease 8-like 1

1

1

High-throughput

0.536

High

1409850

RBM4B
RNA-binding protein 4B

1

1

High-throughput

0.536

High

1437344

LN28A
Protein lin-28 homolog A

1

1

High-throughput

0.536

High

1447642

ZN346
Zinc finger protein 346

1

1

High-throughput

0.536

High

1447644

ABT1
Activator of basal transcription 1

1

2

High-throughput

0.536

High

928231

HAP1
Huntingtin-associated protein 1

1

0

High-throughput

0.518

High

1447641

ZHX1
Zinc fingers and homeoboxes protein 1

1

0

High-throughput

0.518

High

462664

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

4

High-throughput

0.515

High

1372313

H2B1H
Histone H2B type 1-H

1

1

High-throughput

0.515

High

191824

MAGB2
Melanoma-associated antigen B2

1

0

High-throughput

0.513

High

250853

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.513

High

854327

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

868388

CDX1
Homeobox protein CDX-1

1

0

High-throughput

0.513

High

898844

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.513

High

961855

RL37A
Large ribosomal subunit protein eL43

1

0

High-throughput

0.513

High

970127

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

986237

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.513

High

1057921

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.513

High

1150286

TESK1
Dual specificity testis-specific protein kinase 1

1

0

High-throughput

0.513

High

1395713

ZN668
Zinc finger protein 668

1

0

High-throughput

0.513

High

1395828

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.513

High

1412395

ZNF2
Zinc finger protein 2

1

0

High-throughput

0.513

High

191401

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

0

High-throughput

0.493

High

1295147

DZIP1
Cilium assembly protein DZIP1

1

0

High-throughput

0.493

High

1447637

GRHL1
Grainyhead-like protein 1 homolog

1

0

High-throughput

0.493

High

547001

FGF3
Fibroblast growth factor 3

1

2

High-throughput

0.489

High

657315

KALM
Anosmin-1

1

1

High-throughput

0.489

High

1127508

FGFP1
Fibroblast growth factor-binding protein 1

1

1

High-throughput

0.489

High

186050

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

141128

NOP56
Nucleolar protein 56

1

2

High-throughput

0.479

High

182374

WDR46
WD repeat-containing protein 46

1

4

High-throughput

0.479

High

346378

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

6

High-throughput

0.479

High

406691

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.479

High

487788

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

504983

H2AB2
Histone H2A-Bbd type 2/3

1

3

High-throughput

0.479

High

589785

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

696599

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

769268

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

810406

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

883700

CENPA
Histone H3-like centromeric protein A

1

2

High-throughput

0.479

High

981122

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

982843

RS24
Small ribosomal subunit protein eS24

1

1

High-throughput

0.479

High

995293

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.479

High

998844

H31
Histone H3.1

1

2

High-throughput

0.479

High

1017236

H33
Histone H3.3

1

2

High-throughput

0.479

High

1035935

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

1138086

TNIP1
TNFAIP3-interacting protein 1

1

3

High-throughput

0.479

High

1161694

IF16
Gamma-interferon-inducible protein 16

1

2

High-throughput

0.479

High

1311868

DHX40
Probable ATP-dependent RNA helicase DHX40

1

1

High-throughput

0.479

High

1338985

NUP43
Nucleoporin Nup43

1

1

High-throughput

0.479

High

1352773

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

1367364

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

1368640

KAT6A
Histone acetyltransferase KAT6A

1

2

High-throughput

0.479

High

1381598

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

2

High-throughput

0.479

High

1385635

DCPS
m7GpppX diphosphatase

1

1

High-throughput

0.479

High

1415875

DDA1
DET1- and DDB1-associated protein 1

1

1

High-throughput

0.479

High

1447639

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

1

High-throughput

0.479

High

1447640

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1447645

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

129463

MEN1
Menin

1

0

High-throughput

0.458

High

191113

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

223358

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

254437

CC14B
Dual specificity protein phosphatase CDC14B

1

0

High-throughput

0.458

High

558430

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

684513

CTNA2
Catenin alpha-2

1

0

High-throughput

0.458

High

697265

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

872778

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

966915

1433G
14-3-3 protein gamma

1

0

High-throughput

0.458

High

975508

PRS10
26S proteasome regulatory subunit 10B

1

0

High-throughput

0.458

High

1058305

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1107244

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1140916

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1156869

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1313453

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1329893

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.458

High

1338387

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1380766

RL36L
Ribosomal protein eL42-like

1

0

High-throughput

0.458

High

1384887

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1387582

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

0

High-throughput

0.458

High

1414579

DDX23
Probable ATP-dependent RNA helicase DDX23

1

0

High-throughput

0.458

High

1420944

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1428639

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

1432559

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

0

Small-scale

0.458

High

1447647

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

47582

RPSA2
Small ribosomal subunit protein uS2B

1

4

High-throughput

0.445

High

72815

B0UZZ8
WD repeat-containing protein 46

1

4

High-throughput

0.445

High

601871

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.445

High

1239953

CAVN1
Caveolae-associated protein 1

1

1

High-throughput

0.445

High

1433979

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

1447643

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

390959

TRFE
Serotransferrin

3

0

High-throughput

0.347

High

1340361

CEP70
Centrosomal protein of 70 kDa

2

0

High-throughput

0.316

High

1447635

PICK1
PRKCA-binding protein

2

0

High-throughput

0.316

High

1371451

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

0

High-throughput

0.299

High

636772

PTN
Pleiotrophin

1

0

High-throughput

0.282

High

376430

PDGFB
Platelet-derived growth factor subunit B

1

0

High-throughput

0.279

Low

1447646

SIK3
Serine/threonine-protein kinase SIK3

1

0

High-throughput

0.279

Low

1271010

RHOU
Rho-related GTP-binding protein RhoU

1

0

High-throughput

0.261

Low

157895

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

272482

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.249

Low

942912

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.249

Low

1178402

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1255685

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025