Interactor 1: SUCC (P0A836)
Succinate--CoA ligase [ADP-forming] subunit beta (EC 6.2.1.5) (Succinyl-CoA synthetase subunit beta) (SCS-beta)
Gene: SUCC

Interactor 2: SUCD (P0AGE9)
Succinate--CoA ligase [ADP-forming] subunit alpha (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha)
Gene: SUCD

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.918

The method score is based on:

Property Details
Experiments 29176613, 16606699, 19402753, unassigned104, 16858726
Identification Methods affinity chromatography technology, tandem affinity purification, pull down, comigration in non denaturing gel electrophoresis, blue native page
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATP-grasp_2~CoA_binding, ATP-grasp_2~Ligase_CoA, CoA_binding~Ligase_CoA, Ligase_CoA~Ligase_CoA
Common GO terms GO:0004775 - succinate-CoA ligase (ADP-forming) activity
GO:0004776 - succinate-CoA ligase (GDP-forming) activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006099 - tricarboxylic acid cycle
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 388
Ec

1 289
+ Hs
+ Ss
+ Hs
+ Sc
+ Cj
+ Hs

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Last updated: 15 Jul 2024