HitPredict

Interactor 1: TPX (P0A862)
Thiol peroxidase (Tpx) (EC 1.11.1.24) (Peroxiredoxin tpx) (Prx) (Scavengase p20) (Thioredoxin peroxidase) (Thioredoxin-dependent peroxiredoxin)
Gene: TPX

Interactor 2: THIO (P0AA25)
Thioredoxin 1 (Trx-1)
Gene: trxA

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	15004283
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	Redoxin~Thioredoxin
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 168 Ec			1 109
+	Hs
		1026686 PRDX4_HUMAN (13-168): 2.1e-53: 172: 19.76		PDIA6_HUMAN (2-108): 3.32e-35: 126: 26.85
+	So
		188731 BAS1_SPIOL (15-168): 2.83e-50: 163: 24.10		TRXM_SPIOL (3-109): 1.13e-40: 134: 46.73
+	Ss
		852832 Y755_SYNY3 (19-168): 3.45e-53: 169: 27.33		THIO_SYNY3 (7-108): 4.99e-39: 127: 51.96
+	Mm
		956730 PRDX2_MOUSE (14-168): 1.32e-56: 177: 24.70		THIOM_MOUSE (9-108): 4.51e-35: 119: 35.00
+	Mm
		727682 PRDX1_MOUSE (14-168): 5.43e-56: 176: 20.96		THIOM_MOUSE (9-108): 4.51e-35: 119: 35.00
+	Mm
		589514 PRDX3_MOUSE (15-168): 4.46e-55: 175: 25.46		THIOM_MOUSE (9-108): 4.51e-35: 119: 35.00
+	Mm
		139927 PRDX4_MOUSE (13-168): 5.95e-54: 173: 20.36		THIOM_MOUSE (9-108): 4.51e-35: 119: 35.00
+	Hs
		685729 PRDX2_HUMAN (14-168): 1.79e-56: 177: 23.49		TXND5_HUMAN (25-108): 5.99e-30: 112: 31.82
+	Ss
		852848 Y755_SYNY3 (19-168): 3.45e-53: 169: 27.33		THIO1_SYNY3 (11-94): 1.93e-34: 116: 36.91
+	Hs
		1026726 PRDX4_HUMAN (13-168): 2.1e-53: 172: 19.76		TXND5_HUMAN (25-108): 5.99e-30: 112: 31.82
+	Os
		1150818 BAS1_ORYSJ (16-168): 2.4e-50: 163: 22.42		TRXX_ORYSJ (5-109): 3.66e-35: 120: 39.25
+	Hs
		671804 PRDX4_HUMAN (13-168): 2.1e-53: 172: 19.76		PDIA3_HUMAN (2-109): 2.2e-29: 111: 20.54
+	At
		1227668 BAS1B_ARATH (15-168): 1.55e-50: 164: 24.10		TRXX_ARATH (3-108): 3.37e-34: 117: 36.11
+	At
		1227667 BAS1A_ARATH (15-168): 3.94e-50: 163: 24.10		TRXX_ARATH (3-108): 3.37e-34: 117: 36.11
+	Hs
		423216 PRDX4_HUMAN (13-168): 2.1e-53: 172: 19.76		PDIA1_HUMAN (2-106): 3.82e-28: 107: 25.69
+	Ss
		852770 P72697_SYNY3 (17-167): 1.34e-46: 151: 21.02		THIO_SYNY3 (7-108): 4.99e-39: 127: 51.96
+	Sc
		606199 TSA1_YEAST (19-168): 2.1e-49: 159: 23.60		TRX1_YEAST (9-107): 3.5e-34: 115: 40.40
+	Sc
		611720 TSA1_YEAST (19-168): 2.1e-49: 159: 23.60		TRX2_YEAST (9-108): 7.6e-34: 114: 33.00
+	Ss
		852839 P72697_SYNY3 (17-167): 1.34e-46: 151: 21.02		THIO1_SYNY3 (11-94): 1.93e-34: 116: 36.91
+	Ss
		937135 P72697_SYNY3 (17-167): 1.34e-46: 151: 21.02		THIO2_SYNY3 (5-96): 2.15e-22: 85.5: 40.22