Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN
Interactor 2: CDN1B (P46527)
Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1)
Gene: CDKN1B
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.59 | 0.60 | 0.597 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17254966 |
| Identification Methods | affinity chromatography technology, enzymatic study, anti bait coimmunoprecipitation, protein kinase assay |
| Interaction Type | physical association, direct interaction, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008284 - positive regulation of cell population proliferation GO:0008285 - negative regulation of cell population proliferation and 1 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
