Download interactions: TXT MITAB-2.5
| Interaction | Interactor | Experiments | Homologs | Category | Interaction Score |
Confidence |
|---|---|---|---|---|---|---|
|
CDK2
Cyclin-dependent kinase 2 |
59 |
20 |
Small-scale |
0.997 | High |
|
|
CDK4
Cyclin-dependent kinase 4 |
31 |
20 |
Small-scale |
0.993 | High |
|
|
CCNE1
G1/S-specific cyclin-E1 |
25 |
20 |
Small-scale |
0.991 | High |
|
|
CCND1
G1/S-specific cyclin-D1 |
21 |
20 |
Small-scale |
0.988 | High |
|
|
CCNA2
Cyclin-A2 |
17 |
15 |
Small-scale |
0.987 | High |
|
|
CDK5
Cyclin-dependent kinase 5 |
11 |
20 |
Small-scale |
0.983 | High |
|
|
CCND3
G1/S-specific cyclin-D3 |
12 |
20 |
Small-scale |
0.981 | High |
|
|
CDK1
Cyclin-dependent kinase 1 |
11 |
20 |
Small-scale |
0.979 | High |
|
|
CDK6
Cyclin-dependent kinase 6 |
9 |
20 |
Small-scale |
0.970 | High |
|
|
CCNA1
Cyclin-A1 |
8 |
15 |
Small-scale |
0.968 | High |
|
|
CCND2
G1/S-specific cyclin-D2 |
6 |
20 |
Small-scale |
0.952 | High |
|
|
CCNB1
G2/mitotic-specific cyclin-B1 |
6 |
15 |
Small-scale |
0.948 | High |
|
|
AKT1
RAC-alpha serine/threonine-protein kinase |
4 |
8 |
Small-scale |
0.914 | High |
|
|
CCNE2
G1/S-specific cyclin-E2 |
4 |
20 |
Small-scale |
0.910 | High |
|
|
CDK3
Cyclin-dependent kinase 3 |
4 |
20 |
High-throughput |
0.903 | High |
|
|
CDK7
Cyclin-dependent kinase 7 |
3 |
20 |
Small-scale |
0.861 | High |
|
|
CCNB2
G2/mitotic-specific cyclin-B2 |
2 |
15 |
High-throughput |
0.811 | High |
|
|
CDK16
Cyclin-dependent kinase 16 |
2 |
20 |
High-throughput |
0.811 | High |
|
|
KS6A1
Ribosomal protein S6 kinase alpha-1 |
1 |
8 |
Small-scale |
0.770 | High |
|
|
SKP2
S-phase kinase-associated protein 2 |
33 |
7 |
Small-scale |
0.769 | High |
|
|
CSN5
COP9 signalosome complex subunit 5 |
11 |
2 |
Small-scale |
0.756 | High |
|
|
CKS1
Cyclin-dependent kinases regulatory subunit 1 |
6 |
3 |
Small-scale |
0.731 | High |
|
|
MK08
Mitogen-activated protein kinase 8 |
1 |
15 |
Small-scale |
0.724 | High |
|
|
KCC1A
Calcium/calmodulin-dependent protein kinase type 1 |
1 |
1 |
Small-scale |
0.724 | High |
|
|
SPDYA
Speedy protein A |
5 |
2 |
Small-scale |
0.716 | High |
|
|
SGK1
Serine/threonine-protein kinase Sgk1 |
1 |
6 |
Small-scale |
0.710 | High |
|
|
1433T
14-3-3 protein theta |
4 |
8 |
Small-scale |
0.696 | High |
|
|
CDK14
Cyclin-dependent kinase 14 |
1 |
20 |
High-throughput |
0.691 | High |
|
|
CCNO
Cyclin-O |
1 |
20 |
High-throughput |
0.691 | High |
|
|
CDK17
Cyclin-dependent kinase 17 |
1 |
20 |
High-throughput |
0.691 | High |
|
|
CCNB3
G2/mitotic-specific cyclin-B3 |
1 |
17 |
High-throughput |
0.691 | High |
|
|
CUL4A
Cullin-4A |
4 |
6 |
Small-scale |
0.676 | High |
|
|
CUL1
Cullin-1 |
4 |
6 |
Small-scale |
0.674 | High |
|
|
TRAF2
TNF receptor-associated factor 2 |
3 |
6 |
High-throughput |
0.664 | High |
|
|
XPO1
Exportin-1 |
4 |
0 |
Small-scale |
0.662 | High |
|
|
1433B
14-3-3 protein beta/alpha |
3 |
8 |
Small-scale |
0.655 | High |
|
|
MK10
Mitogen-activated protein kinase 10 |
1 |
12 |
Small-scale |
0.647 | High |
|
|
UB2R1
Ubiquitin-conjugating enzyme E2 R1 |
3 |
3 |
Small-scale |
0.639 | High |
|
|
1433E
14-3-3 protein epsilon |
3 |
0 |
Small-scale |
0.636 | High |
|
|
RHOA
Transforming protein RhoA |
2 |
1 |
Small-scale |
0.634 | High |
|
|
CKS2
Cyclin-dependent kinases regulatory subunit 2 |
2 |
3 |
High-throughput |
0.628 | High |
|
|
PIM1
Serine/threonine-protein kinase pim-1 |
1 |
9 |
Small-scale |
0.618 | High |
|
|
GRB2
Growth factor receptor-bound protein 2 |
2 |
5 |
Small-scale |
0.613 | High |
|
|
TSC2
Tuberin |
2 |
3 |
Small-scale |
0.612 | High |
|
|
IMA6
Importin subunit alpha-6 |
2 |
8 |
Small-scale |
0.611 | High |
|
|
MTUS2
Microtubule-associated tumor suppressor candidate 2 |
2 |
1 |
High-throughput |
0.606 | High |
|
|
ZN363
RING finger and CHY zinc finger domain-containing protein 1 |
2 |
0 |
Small-scale |
0.598 | High |
|
|
LYN
Tyrosine-protein kinase Lyn |
1 |
4 |
Small-scale |
0.597 | High |
|
|
UBC9
SUMO-conjugating enzyme UBC9 |
2 |
5 |
Small-scale |
0.595 | High |
|
|
RN123
E3 ubiquitin-protein ligase RNF123 |
2 |
3 |
Small-scale |
0.595 | High |
|
|
SRC
Proto-oncogene tyrosine-protein kinase Src |
1 |
4 |
Small-scale |
0.586 | High |
|
|
ARI1
E3 ubiquitin-protein ligase ARIH1 |
2 |
4 |
Small-scale |
0.585 | High |
|
|
1433F
14-3-3 protein eta |
2 |
8 |
Small-scale |
0.584 | High |
|
|
MCM7
DNA replication licensing factor MCM7 |
1 |
3 |
Small-scale |
0.582 | High |
|
|
JAK2
Tyrosine-protein kinase JAK2 |
1 |
7 |
Small-scale |
0.578 | High |
|
|
COP1
E3 ubiquitin-protein ligase COP1 |
1 |
3 |
Small-scale |
0.578 | High |
|
|
KAT2B
Histone acetyltransferase KAT2B |
1 |
1 |
Small-scale |
0.578 | High |
|
|
WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1 |
1 |
2 |
Small-scale |
0.578 | High |
|
|
RNF6
E3 ubiquitin-protein ligase RNF6 |
1 |
1 |
Small-scale |
0.578 | High |
|
|
IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha |
1 |
10 |
Small-scale |
0.575 | High |
|
|
RBX1
E3 ubiquitin-protein ligase RBX1 |
2 |
0 |
Small-scale |
0.569 | High |
|
|
IMA7
Importin subunit alpha-7 |
1 |
8 |
Small-scale |
0.561 | High |
|
|
IMA5
Importin subunit alpha-5 |
1 |
8 |
Small-scale |
0.561 | High |
|
|
UBE3A
Ubiquitin-protein ligase E3A |
1 |
4 |
Small-scale |
0.561 | High |
|
|
PSB1
Proteasome subunit beta type-1 |
1 |
0 |
Small-scale |
0.554 | High |
|
|
VHL
von Hippel-Lindau disease tumor suppressor |
1 |
2 |
Small-scale |
0.552 | High |
|
|
PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
1 |
0 |
Small-scale |
0.537 | High |
|
|
SIR6
NAD-dependent protein deacylase sirtuin-6 |
1 |
0 |
Small-scale |
0.537 | High |
|
|
GNL3
Guanine nucleotide-binding protein-like 3 |
1 |
0 |
Small-scale |
0.537 | High |
|
|
SPT5H
Transcription elongation factor SPT5 |
1 |
1 |
High-throughput |
0.536 | High |
|
|
BMI1
Polycomb complex protein BMI-1 |
1 |
4 |
High-throughput |
0.536 | High |
|
|
ARL11
ADP-ribosylation factor-like protein 11 |
1 |
1 |
High-throughput |
0.536 | High |
|
|
CAB45
45 kDa calcium-binding protein |
1 |
1 |
High-throughput |
0.536 | High |
|
|
MYC
Myc proto-oncogene protein |
1 |
0 |
Small-scale |
0.529 | High |
|
|
NUP50
Nuclear pore complex protein Nup50 |
1 |
1 |
Small-scale |
0.527 | High |
|
|
IRF1
Interferon regulatory factor 1 |
1 |
0 |
High-throughput |
0.518 | High |
|
|
GDIR1
Rho GDP-dissociation inhibitor 1 |
1 |
0 |
High-throughput |
0.518 | High |
|
|
STMN1
Stathmin |
1 |
2 |
Small-scale |
0.515 | High |
|
|
NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
YKT6
Synaptobrevin homolog YKT6 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
CLPX
ATP-dependent clpX-like chaperone, mitochondrial |
1 |
0 |
High-throughput |
0.513 | High |
|
|
APOD
Apolipoprotein D |
1 |
0 |
High-throughput |
0.513 | High |
|
|
PIP
Prolactin-inducible protein |
1 |
0 |
High-throughput |
0.513 | High |
|
|
TAGL
Transgelin |
1 |
0 |
High-throughput |
0.513 | High |
|
|
PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
IMA3
Importin subunit alpha-3 |
1 |
8 |
Small-scale |
0.501 | High |
|
|
ABL1
Tyrosine-protein kinase ABL1 |
1 |
4 |
Small-scale |
0.501 | High |
|
|
H15
Histone H1.5 |
1 |
2 |
Small-scale |
0.501 | High |
|
|
UB2D2
Ubiquitin-conjugating enzyme E2 D2 |
1 |
2 |
Small-scale |
0.501 | High |
|
|
1433Z
14-3-3 protein zeta/delta |
1 |
8 |
Small-scale |
0.501 | High |
|
|
UBE2B
Ubiquitin-conjugating enzyme E2 B |
1 |
2 |
Small-scale |
0.501 | High |
|
|
UB2L3
Ubiquitin-conjugating enzyme E2 L3 |
1 |
2 |
Small-scale |
0.501 | High |
|
|
H11
Histone H1.1 |
1 |
2 |
Small-scale |
0.501 | High |
|
|
IMA4
Importin subunit alpha-4 |
1 |
8 |
Small-scale |
0.500 | High |
|
|
SCML2
Sex comb on midleg-like protein 2 |
1 |
1 |
Small-scale |
0.500 | High |
|
|
UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
1 |
0 |
Small-scale |
0.493 | High |
|
|
RL27A
Large ribosomal subunit protein uL15 |
1 |
0 |
High-throughput |
0.493 | High |
|
|
TSC1
Hamartin |
1 |
0 |
Small-scale |
0.493 | High |
|
|
BANP
Protein BANP |
1 |
0 |
High-throughput |
0.493 | High |
|
|
THAP1
THAP domain-containing protein 1 |
1 |
0 |
High-throughput |
0.493 | High |
|
|
SKP1
S-phase kinase-associated protein 1 |
2 |
3 |
Small-scale |
0.492 | High |
|
|
DCR1C
Protein artemis |
1 |
0 |
Small-scale |
0.480 | High |
|
|
UBAC1
Ubiquitin-associated domain-containing protein 1 |
1 |
0 |
Small-scale |
0.480 | High |
|
|
WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
UBC
Polyubiquitin-C [Cleaved into: Ubiquitin] |
1 |
6 |
Small-scale |
0.479 | High |
|
|
HSP7C
Heat shock cognate 71 kDa protein |
1 |
4 |
Small-scale |
0.479 | High |
|
|
EGR1
Early growth response protein 1 |
1 |
3 |
High-throughput |
0.479 | High |
|
|
RO52
E3 ubiquitin-protein ligase TRIM21 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
1433S
14-3-3 protein sigma |
1 |
8 |
Small-scale |
0.479 | High |
|
|
TERA
Transitional endoplasmic reticulum ATPase |
1 |
1 |
High-throughput |
0.479 | High |
|
|
1433G
14-3-3 protein gamma |
1 |
8 |
Small-scale |
0.479 | High |
|
|
RNF4
E3 ubiquitin-protein ligase RNF4 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
ACK1
Activated CDC42 kinase 1 |
1 |
7 |
Small-scale |
0.479 | High |
|
|
EP300
Histone acetyltransferase p300 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
CDC20
Cell division cycle protein 20 homolog |
1 |
4 |
Small-scale |
0.479 | High |
|
|
PSMD2
26S proteasome non-ATPase regulatory subunit 2 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
TIF1B
Transcription intermediary factor 1-beta |
1 |
5 |
Small-scale |
0.479 | High |
|
|
CD5R1
Cyclin-dependent kinase 5 activator 1 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
DDB1
DNA damage-binding protein 1 |
1 |
5 |
Small-scale |
0.479 | High |
|
|
UBE2S
Ubiquitin-conjugating enzyme E2 S |
1 |
3 |
Small-scale |
0.479 | High |
|
|
SPDYC
Speedy protein C |
1 |
2 |
Small-scale |
0.479 | High |
|
|
CSN6
COP9 signalosome complex subunit 6 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
SIAH1
E3 ubiquitin-protein ligase SIAH1 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
SPDE1
Speedy protein E1 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
CELF1
CUGBP Elav-like family member 1 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
CSN7B
COP9 signalosome complex subunit 7b |
1 |
1 |
Small-scale |
0.479 | High |
|
|
CREB1
Cyclic AMP-responsive element-binding protein 1 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
BAP31
B-cell receptor-associated protein 31 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
PAX5
Paired box protein Pax-5 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
UBP48
Ubiquitin carboxyl-terminal hydrolase 48 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
DCAF4
DDB1- and CUL4-associated factor 4 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
FBXW7
F-box/WD repeat-containing protein 7 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
TXNIP
Thioredoxin-interacting protein |
1 |
0 |
Small-scale |
0.458 | High |
|
|
YES
Tyrosine-protein kinase Yes |
1 |
4 |
Small-scale |
0.445 | High |
|
|
IMA1
Importin subunit alpha-1 |
1 |
8 |
Small-scale |
0.445 | High |
|
|
PRIO
Major prion protein |
1 |
0 |
High-throughput |
0.426 | High |
|
|
TAU
Microtubule-associated protein tau |
1 |
0 |
High-throughput |
0.426 | High |
|
|
LRCH4
Leucine-rich repeat and calponin homology domain-containing protein 4 |
1 |
0 |
High-throughput |
0.279 | Low |
|
|
A1AG2
Alpha-1-acid glycoprotein 2 |
1 |
0 |
High-throughput |
0.279 | Low |
|
|
APRIO
Alternative prion protein |
1 |
0 |
High-throughput |
0.249 | Low |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
