HitPredict

Interactor 1: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET

Interactor 2: SDF2L (Q9HCN8)
Stromal cell-derived factor 2-like protein 1 (SDF2-like protein 1) (PWP1-interacting protein 8)
Gene: SDF2L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.50	0.565

Property	Details
Experiments	33961781, 35384245
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1114 Hs			1 221
+	Hs
		650428 FGFR3_HUMAN (501-1061): 1.99e-148: 466: 33.16		SDF2L_HUMAN (1-221): 4.36e-95: 278: 100.00
+	Hs
		1157075 NTRK3_HUMAN (336-1018): 1.53e-144: 456: 21.48		SDF2L_HUMAN (1-221): 4.36e-95: 278: 100.00
+	Hs
		363887 EGFR_HUMAN (421-1113): 1.58e-132: 434: 22.19		SDF2L_HUMAN (1-221): 4.36e-95: 278: 100.00
+	Hs
		1157039 NTRK3_HUMAN (336-1018): 1.53e-144: 456: 21.48		SDF2_HUMAN (26-221): 1.48e-84: 251: 65.15
+	Hs
		363755 EGFR_HUMAN (421-1113): 1.58e-132: 434: 22.19		SDF2_HUMAN (26-221): 1.48e-84: 251: 65.15
+	Hs
		648687 FGFR4_HUMAN (535-1054): 2.05e-123: 399: 37.89		SDF2L_HUMAN (1-221): 4.36e-95: 278: 100.00
+	Hs
		777773 VGFR3_HUMAN (677-1012): 1.84e-76: 278: 41.25		SDF2L_HUMAN (1-221): 4.36e-95: 278: 100.00
+	Hs
		787082 FLT3_HUMAN (714-1014): 2.21e-72: 262: 40.00		SDF2L_HUMAN (1-221): 4.36e-95: 278: 100.00