Interactor 1: DLDH (P0A9P0)
Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Glycine cleavage system L protein)
Gene: lpdA

Interactor 2: ODO2 (P0AFG6)
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2) (OGDC-E2) (Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex)
Gene: sucB

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.803

The method score is based on:

Property Details
Experiments 24561554, 15690043
Identification Methods two hybrid, tandem affinity purification, pull down, two hybrid array
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains E3_binding~Pyr_redox_2, E3_binding~Pyr_redox_dim
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006099 - tricarboxylic acid cycle
GO:0045252 - oxoglutarate dehydrogenase complex
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 474
Ec

1 405
+ Hs
+ Hs
+ Hs
+ Dm
+ Gs
+ Sc
+ Sc
+ At
+ Ss
+ Ec
+ At
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024