HitPredict

Interactor 1: HYBG (P0AAM7)
Hydrogenase maturation factor HybG (Hydrogenase-2 operon protein HybG)
Gene: HYBG

Interactor 2: MBHM (P0ACE0)
Hydrogenase-2 large chain (HYD2) (EC 1.12.99.6) (Membrane-bound hydrogenase 2 large subunit) (NiFe hydrogenase)
Gene: hybC

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	19402753, 16412426
Identification Methods	tandem affinity purification, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 82 Ec			1 567
+	Ec
		465949 HYPC_ECOLI (1-75): 3.13e-27: 96.3: 55.84		MBHM_ECOLI (1-567): 0: 798: 100.00
+	Ec
		465956 HYBG_ECOLI (1-82): 1.94e-35: 116: 100.00		MBHL_ECOLI (3-566): 0: 720: 42.81
+	Ec
		465958 HYBG_ECOLI (1-82): 1.94e-35: 116: 100.00		HYCE_ECOLI (4-115): 1.96e-34: 139: 28.57
+	Ec
		465954 HYPC_ECOLI (1-75): 3.13e-27: 96.3: 55.84		HYFG_ECOLI (2-115): 3.04e-35: 141: 27.27
+	Ec
		465950 HYPC_ECOLI (1-75): 3.13e-27: 96.3: 55.84		HYCE_ECOLI (4-115): 1.96e-34: 139: 28.57
+	Nv
		1175709 Q72AR8_NITV2 (1-73): 6.95e-24: 87.5: 28.77		Q72EY8_NITV2 (1-106): 2.77e-38: 146: 30.91
+	Nv
		1175638 Q72AR8_NITV2 (1-73): 6.95e-24: 87.5: 28.77		Q729Q8_NITV2 (4-107): 2.62e-31: 126: 20.76