HitPredict - High confidence protein-protein interactions

Interactor 1: SEQA (P0AFY8)
Negative modulator of initiation of replication
Gene: SEQA

Interactor 2: SEQA (P0AFY8)
Negative modulator of initiation of replication
Gene: SEQA

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.90	0.835

Property	Details
Experiments	24561554, 12379844, 15933720
Identification Methods	two hybrid, molecular sieving, cross-linking study, x-ray crystallography, cosedimentation in solution, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	SeqA~SeqA, SeqA~SeqA_N, SeqA_N~SeqA_N
Common GO terms	GO:0003688 - DNA replication origin binding GO:0005829 - cytosol GO:0006355 - regulation of DNA-templated transcription GO:0007062 - sister chromatid cohesion GO:0009314 - response to radiation and 7 others more... GO:0010385 - double-stranded methylated DNA binding GO:0032297 - negative regulation of DNA-templated DNA replication initiation GO:0032991 - protein-containing complex GO:0042803 - protein homodimerization activity GO:0044729 - hemi-methylated DNA-binding GO:0090143 - nucleoid organization GO:1990097 - SeqA-DNA complex
Homologous interactions	0

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Last updated: 15 Jul 2024