HitPredict

Interactor 1: H2AZ (P0C0S5)
Histone H2A.Z (H2A/z)
Gene: H2AZ1

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28242625, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 128 Hs			1 488
+	Hs
		1270389 H2A1A_HUMAN (5-125): 2.16e-56: 173: 61.48		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1087070 H2A2C_HUMAN (5-127): 3.47e-55: 170: 61.29		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		555567 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		470016 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1038643 H2A1A_HUMAN (5-125): 2.16e-56: 173: 61.48		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1038464 H2A2A_HUMAN (5-125): 4.61e-55: 169: 62.30		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		391684 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		470374 H2A1_HUMAN (5-125): 8.23e-55: 169: 61.48		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		177360 H2A1A_HUMAN (5-125): 2.16e-56: 173: 61.48		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Sc
		693079 H2AZ_YEAST (4-126): 3.32e-39: 129: 65.91		RPD3_YEAST (5-422): 0: 577: 60.95
+	Sp
		140612 H2AZ_SCHPO (18-119): 1.91e-46: 148: 78.43		PHD1_SCHPO (7-411): 0: 519: 52.56
+	Sc
		866882 H2AZ_YEAST (4-126): 3.32e-39: 129: 65.91		HDA1_YEAST (9-330): 1.24e-121: 373: 27.56
+	Hs
		391948 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Hs
		470596 H2A1_HUMAN (5-125): 8.23e-55: 169: 61.48		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04