HitPredict

Interactor 1: H2A1 (P0C0S8)
Histone H2A type 1 (H2A.1) (Histone H2A/ptl)
Gene: H2AC11

Interactor 2: RUVB2 (Q9Y230)
RuvB-like 2 (EC 3.6.4.12) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (51 kDa erythrocyte cytosolic protein) (ECP-51) (INO80 complex subunit J) (Repressing pontin 52) (Reptin 52) (TIP49b) (TIP60-associated protein 54-beta) (TAP54-beta)
Gene: RUVBL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	24463511
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 130 Hs			1 463
+	Hs
		1151396 H2A2A_HUMAN (1-130): 6.74e-68: 202: 98.46		RUVB2_HUMAN (1-463): 0: 718: 100.00
+	Hs
		1216283 H2A2B_HUMAN (1-130): 2.11e-66: 198: 94.62		RUVB2_HUMAN (1-463): 0: 718: 100.00
+	Hs
		555695 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		RUVB2_HUMAN (1-463): 0: 718: 100.00
+	Hs
		470615 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		RUVB1_HUMAN (8-451): 0: 655: 42.67
+	Hs
		555699 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		RUVB1_HUMAN (8-451): 0: 655: 42.67
+	Sc
		392614 H2A2_YEAST (16-128): 2.5e-59: 180: 80.53		RUVB2_YEAST (7-451): 0: 650: 68.76
+	Sc
		392228 H2A1_YEAST (16-127): 4.04e-53: 165: 81.25		RUVB2_YEAST (7-451): 0: 650: 68.76
+	Sc
		392553 H2A2_YEAST (16-128): 2.5e-59: 180: 80.53		RUVB1_YEAST (12-451): 0: 605: 41.72
+	Sc
		392191 H2A1_YEAST (16-127): 4.04e-53: 165: 81.25		RUVB1_YEAST (12-451): 0: 605: 41.72