Protein: RAD52
DNA repair and recombination protein RAD52

Gene: RAD52
Organism: Saccharomyces cerevisiae S288C
Interactions: 68
UniProt ID: P06778

Gene Ontology (top 5):
GO:0000150 - DNA strand exchange activity
GO:0000228 - nuclear chromosome
GO:0000709 - meiotic joint molecule formation
GO:0000722 - telomere maintenance via recombination
GO:0000724 - double-strand break repair via homologous recombination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

448479

RAD59
DNA repair protein RAD59

11

6

Small-scale

0.976

High

448421

RAD52
DNA repair and recombination protein RAD52

7

6

Small-scale

0.952

High

448432

RAD51
DNA repair protein RAD51

34

6

Small-scale

0.770

High

448429

RFA1
Replication factor A protein 1

12

4

Small-scale

0.759

High

448434

RFA2
Replication factor A protein 2

7

3

Small-scale

0.746

High

448480

SMT3
Ubiquitin-like protein SMT3

4

3

Small-scale

0.677

High

448435

RFA3
Replication factor A protein 3

4

0

Small-scale

0.668

High

448424

SRS2
ATP-dependent DNA helicase SRS2

3

1

Small-scale

0.655

High

448469

MSH6
DNA mismatch repair protein MSH6

2

2

High-throughput

0.621

High

448452

SAW1
Single-strand annealing weakened protein 1

2

0

Small-scale

0.603

High

448463

UBC9
SUMO-conjugating enzyme UBC9

2

3

Small-scale

0.594

High

448437

MCM4
DNA replication licensing factor MCM4

2

2

Small-scale

0.586

High

448425

HSC82
ATP-dependent molecular chaperone HSC82

2

2

High-throughput

0.571

High

448433

CDC48
Cell division control protein 48

1

1

Small-scale

0.565

High

448466

MPS1
Serine/threonine-protein kinase MPS1

1

2

Small-scale

0.561

High

381788

H4
Histone H4

2

0

Small-scale

0.559

High

448458

MPH1
ATP-dependent DNA helicase MPH1

2

0

Small-scale

0.559

High

448459

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.559

High

448423

SSB1
Ribosome-associated molecular chaperone SSB1

2

5

High-throughput

0.552

High

448443

ANM1
Protein arginine N-methyltransferase 1

2

0

High-throughput

0.551

High

448468

LGE1
Transcriptional regulatory protein LGE1

2

0

High-throughput

0.547

High

448438

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

1

High-throughput

0.536

High

448453

ALDH5
Aldehyde dehydrogenase 5, mitochondrial

1

1

High-throughput

0.536

High

448464

UFD1
Ubiquitin fusion degradation protein 1

1

0

Small-scale

0.530

High

448442

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

Small-scale

0.513

High

448460

MMM1
Maintenance of mitochondrial morphology protein 1

1

0

Small-scale

0.513

High

448449

RAD55
DNA repair protein RAD55

1

0

Small-scale

0.504

High

448431

RAD57
DNA repair protein RAD57

1

7

Small-scale

0.501

High

448450

AURK
Aurora kinase

1

1

Small-scale

0.501

High

448473

SIZ1
E3 SUMO-protein ligase SIZ1

1

1

Small-scale

0.501

High

408265

GAL1
Galactokinase

1

1

High-throughput

0.500

High

448422

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.500

High

448448

LSM12
Protein LSM12

1

0

High-throughput

0.493

High

448436

MCM5
Minichromosome maintenance protein 5

1

2

Small-scale

0.481

High

448445

MMS4
Crossover junction endonuclease MMS4

1

0

Small-scale

0.480

High

448454

RT105
Regulator of Ty1 transposition protein 105

1

0

Small-scale

0.480

High

448455

SLX8
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8

1

0

Small-scale

0.480

High

448472

MUS81
Crossover junction endonuclease MUS81

1

0

Small-scale

0.480

High

448481

PSY3
Platinum sensitivity protein 3

1

0

Small-scale

0.480

High

391997

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.479

High

448428

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.479

High

448467

H3
Histone H3

1

1

Small-scale

0.479

High

448483

CMR1
DNA damage-binding protein CMR1

1

1

High-throughput

0.479

High

448447

ORC6
Origin recognition complex subunit 6

1

0

Small-scale

0.460

High

448457

CSM2
Chromosome segregation in meiosis protein 2

1

0

Small-scale

0.460

High

448430

BUR1
Serine/threonine-protein kinase BUR1

1

0

Small-scale

0.458

High

448440

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

448451

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

448465

PESC
Pescadillo homolog

1

0

High-throughput

0.458

High

448474

BUR2
Protein BUR2

1

0

Small-scale

0.458

High

448476

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

1

High-throughput

0.457

High

448478

THI21
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21

1

1

High-throughput

0.457

High

448441

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

448446

SSZ1
Ribosome-associated complex subunit SSZ1

1

3

High-throughput

0.445

High

448456

SSB2
Ribosome-associated molecular chaperone SSB2

1

5

High-throughput

0.445

High

380918

H2B1
Histone H2B.1

1

0

High-throughput

0.426

High

448427

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.426

High

448439

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.426

High

448471

YHP1
Homeobox protein YHP1

1

0

High-throughput

0.426

High

448475

BRE1
E3 ubiquitin-protein ligase BRE1

1

0

High-throughput

0.426

High

448482

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.426

High

448426

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.407

High

448477

RTC1
Restriction of telomere capping protein 1

1

0

High-throughput

0.261

Low

448444

SEA4
SEH-associated protein 4

1

0

High-throughput

0.232

Low

448461

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

448462

STU2
Protein STU2

1

0

High-throughput

0.232

Low

448470

GPI17
GPI transamidase component GPI17

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025