HitPredict

Interactor 1: UBB (P0CG47)
Polyubiquitin-B [Cleaved into: Ubiquitin]
Gene: UBB

Interactor 2: TRAF1 (Q13077)
TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
Gene: TRAF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 33961781, 14743216
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 229 Hs			1 416
+	Hs
		475691 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		TRAF1_HUMAN (1-416): 4.57e-172: 489: 100.00
+	Hs
		475011 UBB_HUMAN (1-229): 4.07e-98: 286: 100.00		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Hs
		475253 UBB_HUMAN (1-229): 4.07e-98: 286: 100.00		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Rn
		78208 UBC_RAT (1-181): 2.6e-61: 206: 96.13		B5DFH7_RAT (3-415): 2.07e-119: 358: 36.82
+	Hs
		475684 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Hs
		476627 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Hs
		397944 ISG15_HUMAN (3-154): 1.46e-26: 102: 32.26		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Hs
		924227 RS27A_HUMAN (153-228): 1.76e-44: 147: 100.00		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Rn
		88507 UBC_RAT (1-181): 2.6e-61: 206: 96.13		D3Z9G0_RAT (1-262): 1.31e-12: 71.5: 16.37
+	Mm
		476826 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		TRAF4_MOUSE (27-136): 4.84e-09: 59.9: 18.75
+	Hs
		129527 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		TRAF5_HUMAN (14-261): 1.36e-16: 83.8: 13.91
+	Hs
		476299 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		TRAF4_HUMAN (27-136): 3.55e-09: 60.3: 17.86