HitPredict

Interactor 1: UBB (P0CG47)
Polyubiquitin-B [Cleaved into: Ubiquitin]
Gene: UBB

Interactor 2: FXL15 (Q9H469)
F-box/LRR-repeat protein 15 (F-box only protein 37)
Gene: FBXL15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	F-box~ubiquitin
Common GO terms	GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 229 Hs			1 300
+	Hs
		475018 UBB_HUMAN (1-229): 4.07e-98: 286: 100.00		SKP2_HUMAN (5-293): 1.21e-37: 139: 18.63
+	Dm
		1365167 Q9W418_DROME (1-228): 2.1e-92: 282: 100.00		Q9VF10_DROME (33-272): 3e-37: 142: 24.79
+	Hs
		476369 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		FXL15_HUMAN (1-300): 3.34e-68: 215: 100.00
+	Hs
		475101 UBB_HUMAN (1-229): 4.07e-98: 286: 100.00		FXL16_HUMAN (37-195): 2.77e-11: 65.7: 18.58
+	Sc
		477142 UBI4P_YEAST (1-228): 5.66e-90: 271: 96.05		GRR1_YEAST (168-275): 1.57e-10: 63.9: 22.02
+	At
		1091818 UBQ3_ARATH (1-153): 2.79e-55: 180: 95.43		FBX14_ARATH (6-275): 1.1e-11: 66.9: 15.34
+	Zm
		22945 A0A1D6I4G6_MAIZE (2-76): 1.38e-23: 95.1: 61.33		B4FTC1_MAIZE (4-276): 2.23e-34: 129: 19.48
+	Zm
		22950 A0A1D6I4G6_MAIZE (2-76): 1.38e-23: 95.1: 61.33		K7UXB8_MAIZE (29-274): 7.4e-31: 121: 21.69