HitPredict

Interactor 1: UBB (P0CG47)
Polyubiquitin-B [Cleaved into: Ubiquitin]
Gene: UBB

Interactor 2: UBQL1 (Q9UMX0)
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)
Gene: UBQLN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	25416956
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UBA~ubiquitin, ubiquitin~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0031398 - positive regulation of protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 229 Hs			1 589
+	Hs
		1137416 Q5U5U6_HUMAN (1-229): 4.07e-98: 286: 100.00		UBQL1_HUMAN (1-589): 1.23e-174: 509: 100.00
+	Hs
		475223 UBB_HUMAN (1-229): 4.07e-98: 286: 100.00		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Rn
		1144285 UBC_RAT (1-181): 2.6e-61: 206: 96.13		UBQL1_RAT (1-589): 4.97e-162: 476: 86.15
+	Rn
		88976 UBC_RAT (1-181): 2.6e-61: 206: 96.13		D4AA63_RAT (1-589): 6.84e-149: 445: 65.99
+	Mm
		477045 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		UBQL2_MOUSE (1-589): 8.33e-141: 424: 65.47
+	Dm
		1375397 Q9W418_DROME (1-228): 2.1e-92: 282: 100.00		Q9VXF9_DROME (37-317): 4.08e-51: 184: 17.93
+	Pf
		1181547 Q7KQK2_PLAF7 (1-228): 2.61e-94: 282: 98.68		Q8IJS8_PLAF7 (37-351): 6.06e-38: 146: 15.30
+	Hs
		474985 UBB_HUMAN (1-229): 4.07e-98: 286: 100.00		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Dm
		574862 Q9W418_DROME (1-228): 2.1e-92: 282: 100.00		RL40_DROME (37-126): 7.82e-34: 126: 29.67
+	Rn
		1144200 UBC_RAT (1-181): 2.6e-61: 206: 96.13		BAG6_RAT (24-536): 5.58e-54: 200: 16.84
+	Sc
		477189 UBI4P_YEAST (1-228): 5.66e-90: 271: 96.05		RAD23_YEAST (45-419): 1.17e-31: 128: 17.73
+	Sc
		477360 UBI4P_YEAST (1-228): 5.66e-90: 271: 96.05		DSK2_YEAST (36-243): 8.16e-32: 128: 30.73
+	Mm
		477067 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		BAG6_MOUSE (24-536): 1.29e-49: 187: 16.32
+	Mm
		57049 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		DDI2_MOUSE (47-318): 5.94e-50: 179: 14.39
+	Rn
		48892 UBC_RAT (1-181): 2.6e-61: 206: 96.13		DDI1_RAT (37-318): 7.42e-48: 174: 12.54
+	Hs
		476101 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		DDI1_HUMAN (47-318): 6.39e-53: 187: 15.60
+	Hs
		475888 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		DDI2_HUMAN (47-318): 2.03e-49: 178: 13.52
+	Hs
		475591 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Rn
		924232 UBC_RAT (1-181): 2.6e-61: 206: 96.13		RS27A_RAT (37-107): 1.11e-12: 68: 36.11
+	Hs
		475590 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68