HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24196443
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 143
+	Hs
		476233 UBC_HUMAN (1-685): 0: 846: 100.00		H2A1A_HUMAN (1-125): 8.26e-67: 200: 92.00
+	Hs
		476271 UBC_HUMAN (1-685): 0: 846: 100.00		H2A1J_HUMAN (1-128): 1.45e-66: 199: 92.19
+	Hs
		391519 UBC_HUMAN (1-685): 0: 846: 100.00		H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70
+	Hs
		475912 UBC_HUMAN (1-685): 0: 846: 100.00		H2A2A_HUMAN (1-129): 7e-66: 197: 91.47
+	Hs
		475833 UBC_HUMAN (1-685): 0: 846: 100.00		H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70
+	Sc
		392250 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		H2A2_YEAST (16-124): 4.61e-53: 165: 82.57
+	At
		1092092 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		H2A6_ARATH (1-128): 3.9e-61: 186: 73.64
+	Dm
		950447 R9PY16_DROME (457-685): 5.07e-80: 258: 90.39		H2A_DROME (17-124): 3.82e-60: 183: 90.74
+	Hs
		555403 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00
+	Hs
		391643 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70
+	Hs
		470331 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47
+	Hs
		924034 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		H2A2A_HUMAN (1-129): 7e-66: 197: 91.47
+	Hs
		924049 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		H2A3_HUMAN (1-129): 5.88e-66: 197: 91.47
+	Hs
		260831 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69
+	Hs
		474911 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00
+	Rn
		474085 UBC_RAT (1-108): 1.27e-29: 127: 90.74		H2A2A_RAT (1-129): 7e-66: 197: 91.47
+	Hs
		470393 OASL_HUMAN (1-153): 6.51e-17: 86.3: 29.11		H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47