HitPredict

Interactor 1: A0A8M1Q1X6 (A0A8M1Q1X6)
Ephrin-A3
Gene: efna3a

Interactor 2: Q5ZEW1 (Q5ZEW1)
receptor protein-tyrosine kinase (EC 2.7.10.1)
Gene: epha4a

Species: Danio rerio

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26190107
Identification Methods	avexis
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ephrin~Ephrin_lbd
Common GO terms	GO:0005886 - plasma membrane GO:0007411 - axon guidance
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 220 Dr			1 986
+	Dr
		1140992 Q90YC5_DANRE (21-220): 8.6e-80: 239: 77.07		Q5ZEW1_DANRE (1-986): 0: 1270: 100.00
+	Hs
		595985 EFNA1_HUMAN (9-216): 6.73e-83: 247: 39.23		EPHA4_HUMAN (1-986): 0: 1220: 82.27
+	Hs
		856597 EFNA5_HUMAN (3-189): 1.12e-71: 219: 41.63		EPHA4_HUMAN (1-986): 0: 1220: 82.27
+	Dr
		47531 A0A8M1Q1X6_DANRE (1-207): 4.3e-96: 280: 100.00		A0A8M9PHF0_DANRE (10-986): 0: 1157: 61.24
+	Hs
		856319 EFNA3_HUMAN (19-210): 4.23e-79: 238: 61.58		EPHA7_HUMAN (6-986): 0: 1174: 61.71
+	Dr
		47567 Q90YC5_DANRE (21-220): 8.6e-80: 239: 77.07		A0A8M9PHF0_DANRE (10-986): 0: 1157: 61.24
+	Hs
		856606 EFNA5_HUMAN (3-189): 1.12e-71: 219: 41.63		EPHA7_HUMAN (6-986): 0: 1174: 61.71
+	Hs
		595975 EFNA1_HUMAN (9-216): 6.73e-83: 247: 39.23		EPHA3_HUMAN (26-986): 0: 1143: 61.76
+	Hs
		595976 EFNA1_HUMAN (9-216): 6.73e-83: 247: 39.23		EPHB2_HUMAN (30-986): 0: 1140: 58.13
+	Hs
		665379 EFNA3_HUMAN (19-210): 4.23e-79: 238: 61.58		EPHA3_HUMAN (26-986): 0: 1143: 61.76
+	Dr
		140385 Q90YC5_DANRE (21-220): 8.6e-80: 239: 77.07		EPHA3_DANRE (3-975): 0: 1135: 61.56
+	Hs
		856595 EFNA5_HUMAN (3-189): 1.12e-71: 219: 41.63		EPHA5_HUMAN (2-986): 0: 1154: 62.69
+	Hs
		665382 EFNA5_HUMAN (3-189): 1.12e-71: 219: 41.63		EPHA3_HUMAN (26-986): 0: 1143: 61.76
+	Hs
		856596 EFNA5_HUMAN (3-189): 1.12e-71: 219: 41.63		EPHB1_HUMAN (29-978): 0: 1133: 59.19
+	Hs
		665459 EFNA5_HUMAN (3-189): 1.12e-71: 219: 41.63		EPHA8_HUMAN (30-982): 0: 1082: 56.09
+	Hs
		595974 EFNA1_HUMAN (9-216): 6.73e-83: 247: 39.23		EPHA2_HUMAN (28-982): 0: 1039: 50.83
+	Hs
		665179 EFNA3_HUMAN (19-210): 4.23e-79: 238: 61.58		EPHA2_HUMAN (28-982): 0: 1039: 50.83
+	Hs
		595984 EFNA1_HUMAN (9-216): 6.73e-83: 247: 39.23		EPHB4_HUMAN (14-977): 0: 1011: 50.36
+	Hs
		665181 EFNA5_HUMAN (3-189): 1.12e-71: 219: 41.63		EPHA2_HUMAN (28-982): 0: 1039: 50.83
+	Mm
		139050 EFNA4_MOUSE (3-169): 1.14e-72: 221: 41.42		EPHA1_MOUSE (26-974): 0: 944: 44.50