Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC
Interactor 2: TNAP3 (P21580)
Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 2.3.2.-) (EC 3.4.19.12) (OTU domain-containing protein 7C) (Putative DNA-binding protein A20) (Zinc finger protein A20) [Cleaved into: A20p50; A20p37]
Gene: TNFAIP3
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.984 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19285159, 19373254, 14748687, 22099304, 18029035, 15334086, 27732584, 17961127, 34839354, 21095585, 20622874, 23032187, 23032186, 23827681 |
| Identification Methods | pull down, enzymatic study, x-ray crystallography, two hybrid, protein array |
| Interaction Type | direct interaction, association, physical association, deubiquitination reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | OTU~ubiquitin, ubiquitin~zf-A20 |
| Common GO terms | GO:0002020 - protease binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0070062 - extracellular exosome |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
