HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: RD23B (P54727)
UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58)
Gene: RAD23B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	1.00	0.980

Property	Details
Experiments	28190767, 31699778, 35358511, 38803224, 16196087, 23314748, 23649778, 25752573, 32296183, 12832454, 16712842, unassigned1304, 20059542
Identification Methods	pull down, affinity chromatography technology, two hybrid, x-ray crystallography, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	UBA~ubiquitin, ubiquitin~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 409
+	Hs
		475525 UBC_HUMAN (1-685): 0: 846: 100.00		RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72
+	Hs
		476565 UBC_HUMAN (1-685): 0: 846: 100.00		UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72
+	Hs
		476525 UBC_HUMAN (1-685): 0: 846: 100.00		UBQL2_HUMAN (1-364): 5.93e-51: 182: 13.68
+	Hs
		476438 UBC_HUMAN (1-685): 0: 846: 100.00		UBQL4_HUMAN (1-364): 2.75e-45: 166: 12.71
+	Hs
		475591 UBC_HUMAN (1-685): 0: 846: 100.00		RL40_HUMAN (1-91): 3.57e-33: 122: 28.57
+	Dm
		477540 UBIQP_DROME (1-610): 0: 752: 99.84		Q9VXF9_DROME (1-406): 8.36e-58: 197: 15.39
+	Hs
		475590 UBC_HUMAN (1-685): 0: 846: 100.00		RS27A_HUMAN (1-90): 2.4e-15: 75: 26.67
+	Xl
		1186353 Q7SY79_XENLA (77-685): 0: 744: 99.84		Q9PVN8_XENLA (22-352): 2.31e-44: 164: 13.96
+	Dm
		1375397 Q9W418_DROME (229-685): 0: 557: 99.78		Q9VXF9_DROME (1-406): 8.36e-58: 197: 15.39
+	Sp
		251960 UBI4P_SCHPO (305-685): 1.76e-151: 445: 95.80		RHP23_SCHPO (1-409): 1.78e-77: 245: 34.43
+	Dm
		1362837 Q9W418_DROME (229-685): 0: 557: 99.78		Q9VCD5_DROME (1-238): 9.23e-20: 90.7: 19.92
+	Dm
		574862 Q9W418_DROME (229-685): 0: 557: 99.78		RL40_DROME (1-84): 1.42e-15: 74.6: 29.76
+	Sc
		477189 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		RAD23_YEAST (1-407): 2.12e-72: 233: 28.41
+	At
		1091733 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		RD23C_ARATH (1-409): 1.9e-108: 327: 35.45
+	Pf
		1181547 Q7KQK2_PLAF7 (381-685): 3.65e-126: 380: 98.36		Q8IJS8_PLAF7 (1-408): 2.54e-65: 215: 23.73
+	At
		1091732 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		RD23D_ARATH (1-409): 1.83e-99: 302: 30.00
+	Hs
		1286323 Q96C32_HUMAN (229-533): 1.87e-118: 358: 99.67		UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72
+	At
		96040 UBQ10_ARATH (305-685): 2.63e-153: 453: 95.80		F4I9X6_ARATH (1-80): 3.97e-24: 103: 23.40
+	Pf
		1181539 Q7KQK2_PLAF7 (381-685): 3.65e-126: 380: 98.36		Q7KQK2_PLAF7 (1-79): 4.04e-31: 124: 31.65
+	At
		1247032 RUB2_ARATH (457-608): 1.43e-47: 166: 78.29		DSK2A_ARATH (1-407): 2.58e-59: 203: 17.08