HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: EIF3A (Q14152)
Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta) (eIF3 p167) (eIF3 p180) (eIF3 p185)
Gene: EIF3A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	28190767
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 1382
+	Hs
		476483 UBC_HUMAN (1-685): 0: 846: 100.00		ITSN2_HUMAN (542-870): 1.01e-49: 196: 21.46
+	Hs
		475417 UBC_HUMAN (1-685): 0: 846: 100.00		MYH9_HUMAN (55-1098): 6.44e-45: 180: 9.65
+	Hs
		475816 UBC_HUMAN (1-685): 0: 846: 100.00		ITSN1_HUMAN (539-880): 4.76e-22: 106: 18.54
+	Hs
		475789 UBC_HUMAN (1-685): 0: 846: 100.00		PLEC_HUMAN (497-1343): 1.73e-18: 94.5: 13.97
+	Hs
		475291 UBC_HUMAN (1-685): 0: 846: 100.00		MYH1_HUMAN (83-1022): 3.5e-18: 93.2: 10.72
+	Hs
		475855 UBC_HUMAN (1-685): 0: 846: 100.00		HYDIN_HUMAN (598-868): 4.81e-10: 66.8: 18.53
+	At
		1092094 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		EIF3A_ARATH (3-851): 1.88e-74: 271: 34.22
+	Rn
		1092817 UBC_RAT (1-108): 1.27e-29: 127: 90.74		EIF3A_RAT (1-1382): 1.04e-107: 374: 88.36
+	Mm
		70590 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		B2RR82_MOUSE (532-877): 5.83e-51: 200: 22.69
+	Mm
		476930 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		MYH9_MOUSE (55-1069): 2.38e-45: 182: 10.19
+	Hs
		397813 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MYH9_HUMAN (55-1098): 6.44e-45: 180: 9.65
+	Mm
		476828 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		MYH10_MOUSE (55-1099): 1.67e-35: 150: 9.82
+	Hs
		397814 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MYH10_HUMAN (46-929): 1.09e-34: 147: 10.53
+	Hs
		924144 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		CP250_HUMAN (74-918): 1.12e-17: 92: 10.23
+	Hs
		397977 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		PLEC_HUMAN (497-1343): 1.73e-18: 94.5: 13.97
+	Mm
		477041 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		PLEC_MOUSE (482-1061): 7.55e-13: 76.1: 15.79
+	Mm
		477062 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		ITSN1_MOUSE (607-955): 3.98e-12: 73.4: 15.16
+	Hs
		475174 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		CP250_HUMAN (74-918): 1.12e-17: 92: 10.23
+	Hs
		398052 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MY18A_HUMAN (532-955): 1.34e-09: 65.3: 16.18