HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: TNIP1 (Q15025)
TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN-1) (HIV-1 Nef-interacting protein) (Nef-associated factor 1) (Naf1) (Nip40-1) (Virion-associated nuclear shuttling protein) (VAN) (hVAN)
Gene: TNIP1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.751

Property	Details
Experiments	28190767, 18212736, 19285159, 28319114, 33182596, 34161781, 23032186
Identification Methods	pull down, affinity chromatography technology, x-ray crystallography, protein array
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 636
+	Hs
		476584 UBC_HUMAN (1-685): 0: 846: 100.00		SMC3_HUMAN (278-527): 2.28e-43: 169: 25.09
+	Hs
		476215 UBC_HUMAN (1-685): 0: 846: 100.00		TNIP3_HUMAN (276-538): 4.86e-22: 99.3: 36.67
+	Hs
		475291 UBC_HUMAN (1-685): 0: 846: 100.00		MYH1_HUMAN (4-476): 1.16e-16: 86.5: 10.55
+	Hs
		476092 UBC_HUMAN (1-685): 0: 846: 100.00		RBCC1_HUMAN (161-525): 5.86e-15: 81.1: 17.12
+	Hs
		475816 UBC_HUMAN (1-685): 0: 846: 100.00		ITSN1_HUMAN (92-469): 5.76e-14: 77.7: 11.00
+	Hs
		475279 UBC_HUMAN (1-685): 0: 846: 100.00		LAMC1_HUMAN (4-285): 9.73e-10: 64.2: 9.27
+	Hs
		475417 UBC_HUMAN (1-685): 0: 846: 100.00		MYH9_HUMAN (267-566): 1.17e-09: 63.8: 13.33
+	Sc
		446085 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		MYO1_YEAST (173-528): 5.42e-09: 61.9: 15.11
+	Hs
		923998 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Mm
		477058 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		TNIP1_MOUSE (1-636): 1.34e-64: 226: 82.28
+	Hs
		148651 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12
+	Mm
		476930 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		MYH9_MOUSE (1-554): 1.7e-19: 95.7: 10.65
+	Mm
		476828 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		MYH10_MOUSE (2-506): 2.12e-19: 95.4: 11.16
+	Hs
		924144 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		CP250_HUMAN (63-566): 3.97e-11: 68.8: 11.57
+	Mm
		477062 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		ITSN1_MOUSE (27-390): 6.77e-14: 77.7: 12.43
+	Hs
		397814 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MYH10_HUMAN (210-571): 5.78e-13: 74.6: 10.48
+	Hs
		397813 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MYH9_HUMAN (267-566): 1.17e-09: 63.8: 13.33
+	Hs
		475174 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		CP250_HUMAN (63-566): 3.97e-11: 68.8: 11.57
+	Hs
		148861 OASL_HUMAN (1-153): 6.51e-17: 86.3: 29.11		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12