HitPredict

Interactor 1: A0AQH0 (A0AQH0)
Proteasome subunit beta
Gene: Prosbeta1

Interactor 2: PRS4 (P48601)
26S proteasome regulatory subunit 4 (P26s4)
Gene: Rpt2

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA_lid_3~Proteasome
Common GO terms	GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 224 Dm			1 439
+	Sc
		625948 PSB2_YEAST (9-211): 3.28e-80: 242: 31.22		PRS10_YEAST (9-436): 8.69e-144: 419: 37.82
+	Sc
		751173 PSB1_YEAST (1-208): 1.03e-79: 239: 53.11		PRS10_YEAST (9-436): 8.69e-144: 419: 37.82
+	At
		1227660 PSB6_ARATH (9-208): 8.54e-81: 242: 49.00		PRS4A_ARATH (1-439): 4.1e-137: 402: 77.43
+	At
		286458 PSA4A_ARATH (4-222): 9.08e-79: 238: 12.95		PRS4A_ARATH (1-439): 4.1e-137: 402: 77.43
+	Hs
		656104 PSB9_HUMAN (7-213): 1.88e-78: 236: 50.73		PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55
+	At
		286460 PSA5A_ARATH (4-211): 7.75e-78: 235: 16.20		PRS4A_ARATH (1-439): 4.1e-137: 402: 77.43
+	At
		1114627 PSA5B_ARATH (4-211): 1.49e-77: 234: 16.20		PRS4A_ARATH (1-439): 4.1e-137: 402: 77.43
+	Sc
		625942 PSB2_YEAST (9-211): 3.28e-80: 242: 31.22		PRS4_YEAST (1-439): 7.64e-131: 386: 70.62
+	Sc
		751167 PSB1_YEAST (1-208): 1.03e-79: 239: 53.11		PRS4_YEAST (1-439): 7.64e-131: 386: 70.62
+	Dm
		186126 Q8T8V8_DROME (1-199): 7e-81: 245: 28.00		PRS8_DROME (60-438): 2.22e-125: 371: 45.71
+	Dm
		47592 A0AQH0_DROME (1-224): 1.45e-77: 234: 100.00		PRS8_DROME (60-438): 2.22e-125: 371: 45.71
+	Hs
		656094 PSB9_HUMAN (7-213): 1.88e-78: 236: 50.73		PRS7_HUMAN (8-439): 1.59e-123: 367: 37.16
+	Hs
		656106 PSB9_HUMAN (7-213): 1.88e-78: 236: 50.73		PRS10_HUMAN (49-433): 5.5e-124: 366: 40.26
+	Hs
		656105 PSB9_HUMAN (7-213): 1.88e-78: 236: 50.73		PRS8_HUMAN (43-438): 1.09e-122: 364: 44.28
+	Dm
		47632 A0AQH0_DROME (1-224): 1.45e-77: 234: 100.00		Q9W414_DROME (50-433): 9.11e-123: 364: 41.93
+	Dm
		47615 A0AQH0_DROME (1-224): 1.45e-77: 234: 100.00		Q9V405_DROME (36-432): 2.02e-122: 363: 47.61
+	Hs
		656096 PSB9_HUMAN (7-213): 1.88e-78: 236: 50.73		PRS6B_HUMAN (49-432): 2.56e-121: 361: 48.18
+	Sc
		625923 PSB2_YEAST (9-211): 3.28e-80: 242: 31.22		PRS6B_YEAST (59-421): 2.6e-117: 351: 50.14
+	Sc
		703790 PSB1_YEAST (1-208): 1.03e-79: 239: 53.11		PRS6B_YEAST (59-421): 2.6e-117: 351: 50.14
+	Dm
		47614 A0AQH0_DROME (1-224): 1.45e-77: 234: 100.00		Q9V3V6_DROME (72-430): 1.53e-112: 338: 46.97