HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: PJA1 (Q8NG27)
E3 ubiquitin-protein ligase Praja-1 (Praja1) (EC 2.3.2.27) (RING finger protein 70) (RING-type E3 ubiquitin transferase Praja-1)
Gene: PJA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	16196087
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_2
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 643
+	Hs
		475516 UBC_HUMAN (1-685): 0: 846: 100.00		TTC3_HUMAN (29-635): 4.22e-87: 299: 12.34
+	Hs
		476458 UBC_HUMAN (1-685): 0: 846: 100.00		RNF12_HUMAN (1-641): 4.33e-52: 191: 12.42
+	Hs
		475941 UBC_HUMAN (1-685): 0: 846: 100.00		RN111_HUMAN (33-643): 6.96e-48: 183: 13.06
+	Hs
		282497 UBC_HUMAN (1-685): 0: 846: 100.00		RNF8_HUMAN (383-639): 1.07e-34: 139: 16.85
+	Hs
		476628 UBC_HUMAN (1-685): 0: 846: 100.00		RN115_HUMAN (432-639): 6.28e-33: 130: 21.88
+	Hs
		476063 UBC_HUMAN (1-685): 0: 846: 100.00		ZNRF1_HUMAN (383-633): 8.23e-33: 128: 14.68
+	Hs
		476301 UBC_HUMAN (1-685): 0: 846: 100.00		RN126_HUMAN (545-639): 9.16e-30: 121: 40.00
+	Hs
		476491 UBC_HUMAN (1-685): 0: 846: 100.00		RN181_HUMAN (566-640): 6.22e-29: 114: 38.67
+	At
		1210477 UBQ10_ARATH (305-685): 2.63e-153: 453: 95.80		Q9FM98_ARATH (544-640): 5.25e-31: 127: 31.96
+	At
		1091813 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		RNG1L_ARATH (398-640): 1.79e-33: 132: 18.11
+	At
		1092053 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		Q9FM98_ARATH (544-640): 5.25e-31: 127: 31.96
+	Mm
		476971 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RN111_MOUSE (33-643): 7.42e-56: 206: 14.14
+	At
		477669 UBQ11_ARATH (533-685): 2.54e-59: 201: 95.43		Q9FM98_ARATH (544-640): 5.25e-31: 127: 31.96
+	Mm
		477051 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RNF12_MOUSE (1-640): 2.78e-48: 180: 14.60
+	Hs
		924199 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		RN181_HUMAN (566-640): 6.22e-29: 114: 38.67
+	Mm
		476994 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RN115_MOUSE (432-639): 8.11e-32: 127: 20.89
+	Mm
		476947 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RN126_MOUSE (545-639): 1.67e-30: 123: 41.05
+	Hs
		398150 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		RN115_HUMAN (432-639): 6.28e-33: 130: 21.88
+	Mm
		476987 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RN181_MOUSE (545-640): 5.53e-29: 114: 30.93
+	Hs
		475109 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		ZNRF1_HUMAN (383-633): 8.23e-33: 128: 14.68