HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: OTU7A (Q8TE49)
OTU domain-containing protein 7A (EC 3.4.19.12) (Zinc finger protein Cezanne 2)
Gene: OTUD7A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.845

Property	Details
Experiments	29576527, 31699778, 23827681
Identification Methods	pull down, enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	OTU~ubiquitin, ubiquitin~zf-A20
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 926
+	Hs
		475915 UBC_HUMAN (1-685): 0: 846: 100.00		OTU7B_HUMAN (23-911): 0: 1208: 55.06
+	Mm
		70741 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		OTU7B_MOUSE (23-911): 0: 1199: 55.31
+	Hs
		475060 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		OTU7B_HUMAN (23-911): 0: 1208: 55.06
+	Hs
		475332 UBC_HUMAN (1-685): 0: 846: 100.00		TNAP3_HUMAN (146-404): 3.22e-93: 314: 37.59
+	Hs
		476517 UBC_HUMAN (1-685): 0: 846: 100.00		ZRAN1_HUMAN (148-401): 2.28e-91: 307: 32.16
+	Dr
		48762 F1QHN6_DANRE (229-685): 0: 555: 99.78		ZRN1B_DANRE (140-401): 1.27e-87: 297: 31.74
+	Dm
		1367032 Q9W418_DROME (229-685): 0: 557: 99.78		TRBID_DROME (114-402): 1.99e-84: 289: 29.30
+	Hs
		924207 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		ZRAN1_HUMAN (148-401): 2.28e-91: 307: 32.16
+	Mm
		476820 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		TNAP3_MOUSE (146-507): 7.69e-98: 326: 30.56
+	Mm
		476855 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		ZRAN1_MOUSE (148-401): 1.04e-91: 307: 32.16
+	Hs
		474920 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		TNAP3_HUMAN (146-404): 3.22e-93: 314: 37.59