HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: BAP1 (Q92560)
Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1) (Cerebral protein 6)
Gene: BAP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.917

Property	Details
Experiments	2532544, 26416890, 29576527, 28935764, 33141564
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Peptidase_C12~ubiquitin, UCH_C~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 729
+	Hs
		924096 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		BAP1_HUMAN (1-729): 0: 1185: 100.00
+	Hs
		476639 UBC_HUMAN (1-685): 0: 846: 100.00		UCHL5_HUMAN (5-324): 7.45e-131: 392: 35.71
+	Hs
		475307 UBC_HUMAN (1-685): 0: 846: 100.00		UCHL3_HUMAN (2-236): 3.91e-78: 251: 23.05
+	Hs
		456475 UBC_HUMAN (1-685): 0: 846: 100.00		UCHL1_HUMAN (7-236): 1.69e-68: 226: 22.27
+	Sc
		477215 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBL1_YEAST (2-236): 2.58e-51: 180: 18.70
+	Mm
		477056 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UCHL5_MOUSE (5-324): 6.54e-131: 392: 36.31
+	Hs
		398154 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		UCHL5_HUMAN (5-324): 7.45e-131: 392: 35.71
+	Mm
		477030 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UCHL3_MOUSE (2-236): 5.65e-78: 251: 23.05
+	Hs
		456536 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		UCHL1_HUMAN (7-236): 1.69e-68: 226: 22.27
+	Mm
		476730 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UCHL4_MOUSE (2-236): 1.18e-75: 245: 22.76
+	Hs
		474910 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		UCHL3_HUMAN (2-236): 3.91e-78: 251: 23.05
+	Hs
		548107 Q5U5U6_HUMAN (1-77): 7.83e-26: 108: 98.70		UCHL3_HUMAN (2-236): 3.91e-78: 251: 23.05
+	Mm
		477047 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UCHL1_MOUSE (7-236): 9.46e-67: 221: 22.69
+	Rn
		962731 UBC_RAT (1-108): 1.27e-29: 127: 90.74		UCHL1_RAT (7-236): 9.46e-67: 221: 22.69
+	Hs
		456474 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		UCHL1_HUMAN (7-236): 1.69e-68: 226: 22.27