HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: WRIP1 (Q96S55)
ATPase WRNIP1 (EC 3.6.1.-) (Werner helicase-interacting protein 1)
Gene: WRNIP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.927

Property	Details
Experiments	28190767, 38803224, 23314748, 17550899, 25872870
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	AAA~ubiquitin, ubiquitin~zf-WRNIP1_ubi
Common GO terms	GO:0005634 - nucleus
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 665
+	Hs
		475409 UBC_HUMAN (1-685): 0: 846: 100.00		RFC2_HUMAN (200-541): 1.91e-66: 224: 18.44
+	Hs
		475441 UBC_HUMAN (1-685): 0: 846: 100.00		RFC5_HUMAN (221-559): 2.63e-64: 217: 19.10
+	Hs
		475442 UBC_HUMAN (1-685): 0: 846: 100.00		RFC3_HUMAN (227-505): 2.05e-60: 207: 14.10
+	Mm
		476946 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		WRIP1_MOUSE (1-665): 0: 634: 94.74
+	Sc
		477307 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		WRIP1_YEAST (124-654): 1.92e-119: 370: 38.12