HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: RNF12 (Q9NVW2)
E3 ubiquitin-protein ligase RLIM (EC 2.3.2.27) (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (RING finger protein 12) (RING-type E3 ubiquitin transferase RLIM) (Renal carcinoma antigen NY-REN-43)
Gene: RLIM

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	32416094, 16196087
Identification Methods	enzymatic study, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 624
+	Hs
		476073 UBC_HUMAN (1-685): 0: 846: 100.00		PJA1_HUMAN (79-617): 4.34e-48: 180: 15.56
+	Hs
		475941 UBC_HUMAN (1-685): 0: 846: 100.00		RN111_HUMAN (73-622): 4.75e-44: 171: 10.53
+	Hs
		476347 UBC_HUMAN (1-685): 0: 846: 100.00		RNF38_HUMAN (132-613): 1.34e-43: 165: 14.58
+	Hs
		475516 UBC_HUMAN (1-685): 0: 846: 100.00		TTC3_HUMAN (172-622): 2.67e-40: 160: 11.40
+	Hs
		282497 UBC_HUMAN (1-685): 0: 846: 100.00		RNF8_HUMAN (330-614): 2.23e-34: 138: 11.15
+	Hs
		476301 UBC_HUMAN (1-685): 0: 846: 100.00		RN126_HUMAN (364-621): 1.27e-33: 132: 18.08
+	Hs
		476628 UBC_HUMAN (1-685): 0: 846: 100.00		RN115_HUMAN (423-621): 3.75e-33: 131: 20.90
+	Hs
		476007 UBC_HUMAN (1-685): 0: 846: 100.00		GOLI_HUMAN (522-617): 2.5e-31: 128: 33.01
+	Mm
		477051 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RNF12_MOUSE (1-624): 1.04e-103: 328: 84.14
+	At
		1091813 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		RNG1L_ARATH (415-619): 2e-30: 124: 16.82
+	Mm
		476971 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RN111_MOUSE (77-622): 4.89e-48: 183: 11.88
+	Hs
		924057 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		GOLI_HUMAN (522-617): 2.5e-31: 128: 33.01
+	Mm
		476994 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RN115_MOUSE (423-621): 3.88e-35: 136: 20.40
+	Mm
		476947 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RN126_MOUSE (364-621): 3.32e-32: 128: 17.69
+	Hs
		398150 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		RN115_HUMAN (423-621): 3.75e-33: 131: 20.90
+	Hs
		475173 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		RN126_HUMAN (364-621): 1.27e-33: 132: 18.08
+	Mm
		476987 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RN181_MOUSE (545-620): 2.57e-28: 113: 27.63
+	Hs
		475090 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		GOLI_HUMAN (522-617): 2.5e-31: 128: 33.01
+	Zm
		79051 B6SKC9_MAIZE (514-679): 1.23e-22: 104: 25.88		C0P544_MAIZE (416-614): 2.14e-33: 129: 21.13