HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: AKIB1 (Q9P2G1)
Ankyrin repeat and IBR domain-containing protein 1 (EC 2.3.2.31)
Gene: ANKIB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.80	0.752

Property	Details
Experiments	31699778, 38803224, 16196087
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ariadne~ubiquitin, IBR~ubiquitin
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 1089
+	Hs
		476630 UBC_HUMAN (1-685): 0: 846: 100.00		ARI1_HUMAN (218-748): 1.61e-159: 485: 25.19
+	Hs
		312458 UBC_HUMAN (1-685): 0: 846: 100.00		ARI2_HUMAN (179-730): 9.58e-147: 450: 24.19
+	Hs
		475939 UBC_HUMAN (1-685): 0: 846: 100.00		RN19B_HUMAN (315-578): 3.99e-67: 242: 22.51
+	Hs
		476187 UBC_HUMAN (1-685): 0: 846: 100.00		RNF31_HUMAN (194-576): 1.63e-63: 237: 13.58
+	Hs
		475976 UBC_HUMAN (1-685): 0: 846: 100.00		R144B_HUMAN (313-555): 1.15e-62: 217: 20.73
+	Hs
		475494 UBC_HUMAN (1-685): 0: 846: 100.00		R144A_HUMAN (329-555): 1.65e-59: 208: 25.65
+	Hs
		226335 UBC_HUMAN (1-685): 0: 846: 100.00		PRKN_HUMAN (336-554): 2.33e-47: 178: 22.65
+	Dm
		477528 UBIQP_DROME (1-610): 0: 752: 99.84		LUBEL_DROME (205-577): 2.32e-62: 235: 15.31
+	Dm
		1214032 Q9W418_DROME (229-685): 0: 557: 99.78		LUBEL_DROME (205-577): 2.32e-62: 235: 15.31
+	Sc
		477225 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		HEL1_YEAST (177-726): 3.1e-129: 406: 22.20
+	Hs
		312457 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		ARI2_HUMAN (179-730): 9.58e-147: 450: 24.19
+	At
		1092233 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		Q9M1E9_ARATH (184-597): 3.64e-73: 250: 15.04
+	Hs
		475094 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		CUL9_HUMAN (216-747): 1.46e-112: 388: 22.22
+	Mm
		476959 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RNF31_MOUSE (185-576): 4.48e-60: 226: 14.32
+	Hs
		475069 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		RN19B_HUMAN (315-578): 3.99e-67: 242: 22.51
+	Hs
		227107 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		PRKN_HUMAN (336-554): 2.33e-47: 178: 22.65
+	Rn
		1144287 UBC_RAT (1-108): 1.27e-29: 127: 90.74		PRKN_RAT (336-554): 1.66e-47: 178: 21.30
+	Hs
		226251 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		PRKN_HUMAN (336-554): 2.33e-47: 178: 22.65
+	Hs
		171468 UBD_HUMAN (155-304): 5.41e-28: 112: 32.05		PRKN_HUMAN (336-554): 2.33e-47: 178: 22.65
+	Hs
		226334 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		PRKN_HUMAN (336-554): 2.33e-47: 178: 22.65