Protein: ASCL1
Achaete-scute homolog 1 (ASH-1) (hASH1) (Class A basic helix-loop-helix protein 46) (bHLHa46)

Gene: ASCL1
Organism: Homo sapiens
Interactions: 38
UniProt ID: P50553

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

587432

TFE2
Transcription factor E2-alpha

3

20

Small-scale

0.852

High

587028

ITF2
Transcription factor 4

2

20

Small-scale

0.821

High

896697

HTF4
Transcription factor 12

1

20

High-throughput

0.691

High

896686

MEF2A
Myocyte-specific enhancer factor 2A

2

4

Small-scale

0.625

High

896698

UBQL2
Ubiquilin-2

2

4

High-throughput

0.606

High

896699

UBQL1
Ubiquilin-1

2

4

High-throughput

0.553

High

896700

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

2

6

High-throughput

0.553

High

896695

RSPH1
Radial spoke head 1 homolog

1

1

High-throughput

0.541

High

652293

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

1

High-throughput

0.536

High

667656

CDK2
Cyclin-dependent kinase 2

1

1

High-throughput

0.536

High

713346

SPB3
Serpin B3

1

4

High-throughput

0.536

High

876572

NEST
Nestin

1

7

High-throughput

0.536

High

156250

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

0

High-throughput

0.513

High

629084

CCNA2
Cyclin-A2

1

0

High-throughput

0.513

High

154653

ARI1A
AT-rich interactive domain-containing protein 1A

1

10

Small-scale

0.500

High

896696

SMRC1
SWI/SNF complex subunit SMARCC1

1

2

Small-scale

0.500

High

476496

STS
Steryl-sulfatase

1

1

High-throughput

0.489

High

874762

SPB4
Serpin B4

1

4

High-throughput

0.489

High

895425

SPB8
Serpin B8

1

4

High-throughput

0.489

High

896682

ARSF
Arylsulfatase F

1

1

High-throughput

0.489

High

896684

EPIPL
Epiplakin

1

7

High-throughput

0.489

High

896685

NGAL
Neutrophil gelatinase-associated lipocalin

1

1

High-throughput

0.489

High

896688

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

1

High-throughput

0.489

High

896701

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

1

1

High-throughput

0.489

High

896687

MEF2C
Myocyte-specific enhancer factor 2C

1

4

Small-scale

0.481

High

896690

MEF2D
Myocyte-specific enhancer factor 2D

1

4

Small-scale

0.481

High

892744

CDN1C
Cyclin-dependent kinase inhibitor 1C

1

2

Small-scale

0.479

High

896689

EP300
Histone acetyltransferase p300

1

19

Small-scale

0.479

High

869712

MTR1A
Melatonin receptor type 1A

1

1

High-throughput

0.464

High

75660

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

2

High-throughput

0.437

High

896693

PSD4
PH and SEC7 domain-containing protein 4

1

4

High-throughput

0.437

High

69483

A2ML1
Alpha-2-macroglobulin-like protein 1

1

2

High-throughput

0.407

High

896683

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

0

High-throughput

0.282

High

276571

LX12B
Arachidonate 12-lipoxygenase, 12R-type

1

0

High-throughput

0.279

Low

627117

TYPH
Thymidine phosphorylase

1

0

High-throughput

0.279

Low

896691

PA24E
Cytosolic phospholipase A2 epsilon

1

0

High-throughput

0.279

Low

896692

S1A7A
Protein S100-A7A

1

0

High-throughput

0.279

Low

896694

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025