Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: HDAC6 (Q9UBN7)
Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Protein deacetylase HDAC6) (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)
Gene: HDAC6

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 25429107, 25342804, 24035499, 28540657, 35476995, 36114200, 17512543, 15171253, 28190767, 27182664, 34642328, 21690293, 20129057, 24023063, 12354939
Identification Methods affinity chromatography technology, pull down, protein complementation assay, enzymatic study, proximity labelling technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ubiquitin~zf-UBP
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0031625 - ubiquitin protein ligase binding
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 685
Hs

1 1215
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Zm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024