HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: POLH (Q9Y253)
DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein)
Gene: POLH

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.734

Property	Details
Experiments	16763556, 16357261, 25766642, 31699778, 20129057, 17304240
Identification Methods	pull down, two hybrid, affinity chromatography technology, nuclear magnetic resonance
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 713
+	Hs
		476567 UBC_HUMAN (1-685): 0: 846: 100.00		POLI_HUMAN (2-709): 6.53e-133: 411: 22.88
+	Hs
		476512 UBC_HUMAN (1-685): 0: 846: 100.00		REV1_HUMAN (2-690): 2.19e-121: 394: 18.00
+	Sc
		477433 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		POLH_YEAST (8-561): 2.15e-116: 365: 20.42
+	Mm
		476678 UBB_MOUSE (457-685): 2.3e-86: 275: 99.56		POLK_MOUSE (6-669): 8.67e-128: 401: 20.18
+	Sc
		477092 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		REV1_YEAST (8-515): 3.7e-65: 234: 15.06
+	Mm
		476850 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		POLI_MOUSE (4-593): 4.2e-145: 442: 24.56
+	Mm
		476951 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		REV1_MOUSE (2-702): 1.27e-125: 405: 19.10
+	Mm
		477038 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		POLK_MOUSE (6-669): 8.67e-128: 401: 20.18
+	Hs
		475244 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		POLI_HUMAN (2-709): 6.53e-133: 411: 22.88