HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: EPN1 (Q9Y6I3)
Epsin-1 (EH domain-binding mitotic phosphoprotein) (EPS-15-interacting protein 1)
Gene: EPN1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.734

Property	Details
Experiments	16497222, 28190767, 31699778, 38803224, 19285159, 23314748
Identification Methods	pull down, protein array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 576
+	Hs
		476358 UBC_HUMAN (1-685): 0: 846: 100.00		EPN3_HUMAN (1-571): 3.16e-55: 199: 40.16
+	Hs
		307500 UBC_HUMAN (1-685): 0: 846: 100.00		EPN2_HUMAN (1-566): 6.51e-54: 195: 38.02
+	Dm
		477525 UBIQP_DROME (1-610): 0: 752: 99.84		Q7KU90_DROME (1-571): 4.4e-58: 209: 31.51
+	Hs
		475943 UBC_HUMAN (1-685): 0: 846: 100.00		OTOG_HUMAN (190-573): 2.44e-15: 82: 10.91
+	Sc
		477505 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		ENT1_YEAST (3-228): 6.81e-62: 212: 36.73
+	Sc
		477449 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		ENT2_YEAST (3-538): 7.67e-59: 208: 19.59
+	Dm
		1182371 R9PY16_DROME (457-685): 5.07e-80: 258: 90.39		Q7KU90_DROME (1-571): 4.4e-58: 209: 31.51
+	Hs
		924231 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		EPN1_HUMAN (1-576): 4.42e-90: 290: 100.00
+	Hs
		111209 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		I6L9I8_HUMAN (1-288): 1.38e-92: 288: 54.43
+	At
		1091714 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		EPN2_ARATH (2-574): 1.39e-39: 156: 21.89
+	Rn
		291394 UBC_RAT (1-108): 1.27e-29: 127: 90.74		EPN1_RAT (1-576): 2.54e-91: 293: 94.27
+	Mm
		476869 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		EPN1_MOUSE (1-576): 1.93e-88: 286: 94.44
+	Hs
		397968 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		EPN4_HUMAN (3-561): 1.44e-89: 290: 24.14
+	Mm
		476910 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		EPN2_MOUSE (1-562): 4.4e-64: 222: 41.91
+	Hs
		924159 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		EPN3_HUMAN (1-571): 3.16e-55: 199: 40.16
+	Hs
		307522 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		EPN2_HUMAN (1-566): 6.51e-54: 195: 38.02
+	Hs
		475183 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		EPN3_HUMAN (1-571): 3.16e-55: 199: 40.16
+	Rn
		1144063 UBC_RAT (1-108): 1.27e-29: 127: 90.74		SYNJ1_RAT (246-575): 3.51e-15: 81.2: 14.67