HitPredict

Interactor 1: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Interactor 2: UBP4 (P35123)
Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Ubiquitous nuclear protein)
Gene: Usp4

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	26811477, 28190767
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	DUSP~ubiquitin, UCH~ubiquitin
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 734 Mm			1 962
+	Rn
		70290 UBC_RAT (1-724): 0: 898: 97.51		UBP4_RAT (1-962): 0: 916: 95.74
+	Hs
		475693 UBC_HUMAN (77-724): 0: 790: 97.22		UBP4_HUMAN (1-962): 0: 888: 90.76
+	Mm
		476926 UBC_MOUSE (1-734): 0: 912: 100.00		UBP15_MOUSE (1-924): 0: 749: 56.84
+	Mm
		476963 UBC_MOUSE (1-734): 0: 912: 100.00		UBP11_MOUSE (5-955): 0: 700: 42.27
+	Hs
		475502 UBC_HUMAN (77-724): 0: 790: 97.22		UBP11_HUMAN (6-923): 0: 702: 45.05
+	Mm
		476793 UBC_MOUSE (1-734): 0: 912: 100.00		UBP19_MOUSE (217-939): 2.72e-132: 433: 28.99
+	Hs
		301354 UBC_HUMAN (77-724): 0: 790: 97.22		UBP19_HUMAN (217-953): 6.99e-159: 503: 30.78
+	Mm
		476967 UBC_MOUSE (1-734): 0: 912: 100.00		UBP16_MOUSE (251-921): 1.14e-96: 325: 17.65
+	Mm
		476897 UBC_MOUSE (1-734): 0: 912: 100.00		UBP37_MOUSE (146-943): 2.06e-88: 305: 14.29
+	Hs
		475954 UBC_HUMAN (77-724): 0: 790: 97.22		UBP31_HUMAN (250-922): 3.39e-120: 400: 27.08
+	Mm
		476865 UBC_MOUSE (1-734): 0: 912: 100.00		UBP8_MOUSE (577-930): 1.68e-60: 226: 22.69
+	Rn
		1137288 UBC_RAT (1-724): 0: 898: 97.51		UBP2_RAT (529-924): 2.42e-59: 216: 21.00
+	Mm
		476741 UBC_MOUSE (1-734): 0: 912: 100.00		UBP46_MOUSE (637-923): 2.29e-55: 198: 20.77
+	Hs
		475957 UBC_HUMAN (77-724): 0: 790: 97.22		UBP45_HUMAN (294-921): 8.21e-80: 278: 17.53
+	Hs
		475440 UBC_HUMAN (77-724): 0: 790: 97.22		UBP8_HUMAN (577-930): 1.26e-60: 227: 22.41
+	Hs
		271022 UBC_HUMAN (77-724): 0: 790: 97.22		UBP2_HUMAN (617-924): 7.4e-60: 217: 24.92
+	Mm
		476939 UBC_MOUSE (1-734): 0: 912: 100.00		UBP3_MOUSE (303-482): 2.22e-16: 85.5: 29.74
+	Hs
		475566 UBC_HUMAN (77-724): 0: 790: 97.22		UBP46_HUMAN (637-923): 2.29e-55: 198: 20.77
+	Mm
		101489 UBC_MOUSE (1-734): 0: 912: 100.00		UBP32_MOUSE (491-804): 2.53e-10: 67: 10.88
+	Hs
		475403 UBC_HUMAN (77-724): 0: 790: 97.22		UBP6_HUMAN (856-959): 1.84e-23: 109: 33.65