HitPredict

Interactor 1: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Interactor 2: RN181 (Q9CY62)
E3 ubiquitin-protein ligase RNF181 (EC 2.3.2.27) (RING finger protein 181)
Gene: Rnf181

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	28190767
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_2
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 734 Mm			1 165
+	Mm
		476994 UBC_MOUSE (1-734): 0: 912: 100.00		RN115_MOUSE (54-161): 8.07e-28: 106: 34.55
+	Mm
		476947 UBC_MOUSE (1-734): 0: 912: 100.00		RN126_MOUSE (54-142): 1.42e-25: 101: 36.26
+	Hs
		476491 UBC_HUMAN (77-724): 0: 790: 97.22		RN181_HUMAN (1-165): 7.61e-40: 133: 78.92
+	Hs
		476301 UBC_HUMAN (77-724): 0: 790: 97.22		RN126_HUMAN (34-132): 2.95e-31: 115: 34.31
+	Hs
		476628 UBC_HUMAN (77-724): 0: 790: 97.22		RN115_HUMAN (54-161): 1.29e-28: 108: 35.46
+	Hs
		476073 UBC_HUMAN (77-724): 0: 790: 97.22		PJA1_HUMAN (64-135): 3.54e-26: 105: 35.53
+	At
		1210477 UBQ10_ARATH (305-724): 5.09e-169: 495: 91.91		Q9FM98_ARATH (11-164): 4.69e-29: 111: 32.26
+	At
		1091813 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		RNG1L_ARATH (18-142): 6.52e-32: 117: 34.38
+	At
		1092053 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		Q9FM98_ARATH (11-164): 4.69e-29: 111: 32.26
+	At
		1092416 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		ATL18_ARATH (88-129): 1.98e-12: 62.8: 61.36
+	At
		477669 UBQ11_ARATH (533-724): 1.57e-68: 226: 86.98		Q9FM98_ARATH (11-164): 4.69e-29: 111: 32.26
+	Hs
		924199 RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00		RN181_HUMAN (1-165): 7.61e-40: 133: 78.92
+	Hs
		475216 UBB_HUMAN (1-77): 3.45e-27: 112: 98.70		RN181_HUMAN (1-165): 7.61e-40: 133: 78.92
+	Hs
		475173 UBB_HUMAN (1-77): 3.45e-27: 112: 98.70		RN126_HUMAN (34-132): 2.95e-31: 115: 34.31
+	Hs
		398150 ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69		RN115_HUMAN (54-161): 1.29e-28: 108: 35.46