HitPredict

Interactor 1: HSP77 (P0CS90)
Import motor subunit, mitochondrial (EC 3.6.4.10) (Endonuclease SceI 75 kDa subunit) (Endo.SceI 75 kDa subunit) (mtHSP70)
Gene: SSC1

Interactor 2: ACON (P19414)
Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase)
Gene: ACO1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	29651044, 25792736, 37968396, 32051233
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0042645 - mitochondrial nucleoid
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 654 Sc			1 778
+	Hs
		504641 HSP7C_HUMAN (28-634): 0: 861: 48.87		ACON_HUMAN (9-777): 0: 995: 66.71
+	Sc
		478208 HSP77_YEAST (1-654): 0: 896: 100.00		ACON2_YEAST (1-777): 0: 908: 54.34
+	Hs
		751796 GRP75_HUMAN (16-654): 0: 788: 64.90		ACON_HUMAN (9-777): 0: 995: 66.71
+	Hs
		503427 HSP7C_HUMAN (28-634): 0: 861: 48.87		ACOHC_HUMAN (74-778): 0: 786: 27.59
+	At
		612314 HS701_ARATH (25-654): 0: 857: 46.72		ACO2M_ARATH (63-777): 0: 784: 26.39
+	Hs
		502472 BIP_HUMAN (30-632): 0: 542: 50.82		ACON_HUMAN (9-777): 0: 995: 66.71
+	At
		1339699 HSP7G_ARATH (28-632): 0: 608: 55.85		ACO3M_ARATH (84-778): 0: 813: 26.67
+	Sc
		478348 HSP77_YEAST (1-654): 0: 896: 100.00		LYS4_YEAST (57-729): 4.11e-167: 500: 24.20
+	Ec
		457316 DNAK_ECOLI (30-629): 0: 655: 59.50		LEUC_ECOLI (64-503): 2.96e-148: 443: 25.48
+	Sc
		826563 HSP7Q_YEAST (12-637): 0: 585: 52.08		LYS4_YEAST (57-729): 4.11e-167: 500: 24.20
+	Ec
		459218 DNAK_ECOLI (30-629): 0: 655: 59.50		LEUD_ECOLI (570-766): 4.93e-39: 145: 19.80