HitPredict

Interactor 1: HSP77 (P0CS90)
Import motor subunit, mitochondrial (EC 3.6.4.10) (Endonuclease SceI 75 kDa subunit) (Endo.SceI 75 kDa subunit) (mtHSP70)
Gene: SSC1

Interactor 2: PP11 (P20604)
Serine/threonine-protein phosphatase PP1-1 (EC 3.1.3.16)
Gene: SIT4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	11805837, 19536198
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 654 Sc			1 311
+	Sc
		618775 HSP7E_YEAST (17-646): 0: 969: 82.22		PP2A1_YEAST (6-311): 1.72e-175: 491: 54.58
+	Sc
		477923 HSP77_YEAST (1-654): 0: 896: 100.00		PP2A1_YEAST (6-311): 1.72e-175: 491: 54.58
+	Hs
		503837 HSP7C_HUMAN (28-634): 0: 861: 48.87		PP2AB_HUMAN (2-311): 0: 520: 57.10
+	Hs
		503863 HSP7C_HUMAN (28-634): 0: 861: 48.87		PP2AA_HUMAN (1-311): 0: 519: 56.59
+	Hs
		713936 HS71L_HUMAN (26-654): 0: 868: 46.90		PP1A_HUMAN (6-305): 0: 506: 42.86
+	Hs
		905943 Q53FA3_HUMAN (26-654): 0: 868: 46.90		PP1A_HUMAN (6-305): 0: 506: 42.86
+	Hs
		713915 HS71L_HUMAN (26-654): 0: 868: 46.90		PP1G_HUMAN (11-301): 0: 503: 43.73
+	Hs
		503821 HSP7C_HUMAN (28-634): 0: 861: 48.87		PP1A_HUMAN (6-305): 0: 506: 42.86
+	Hs
		503566 HSP7C_HUMAN (28-634): 0: 861: 48.87		PP1G_HUMAN (11-301): 0: 503: 43.73
+	Mm
		571849 HS71B_MOUSE (28-654): 0: 855: 46.59		PP1A_MOUSE (6-305): 0: 507: 42.53
+	Mm
		571852 HS71B_MOUSE (28-654): 0: 855: 46.59		PP1G_MOUSE (11-301): 0: 503: 43.73
+	Hs
		737670 HSP72_HUMAN (28-654): 0: 850: 47.20		PP1G_HUMAN (11-301): 0: 503: 43.73
+	Mm
		751908 GRP75_MOUSE (16-654): 0: 786: 64.90		PP1A_MOUSE (6-305): 0: 507: 42.53
+	Hs
		135348 HSP7C_HUMAN (28-634): 0: 861: 48.87		PPP6_HUMAN (7-292): 3.77e-148: 419: 65.39
+	Sc
		594366 HSP7Q_YEAST (12-637): 0: 585: 52.08		PP11_YEAST (1-311): 0: 506: 100.00
+	Sc
		618798 HSP7Q_YEAST (12-637): 0: 585: 52.08		PP2A1_YEAST (6-311): 1.72e-175: 491: 54.58
+	Mm
		588710 BIP_MOUSE (30-632): 0: 543: 50.82		PP1A_MOUSE (6-305): 0: 507: 42.53
+	Hs
		501916 BIP_HUMAN (30-632): 0: 542: 50.82		PP1A_HUMAN (6-305): 0: 506: 42.86
+	Hs
		501766 BIP_HUMAN (30-632): 0: 542: 50.82		PP1G_HUMAN (11-301): 0: 503: 43.73
+	Hs
		135347 BIP_HUMAN (30-632): 0: 542: 50.82		PPP6_HUMAN (7-292): 3.77e-148: 419: 65.39