HitPredict

Interactor 1: ESYT2 (A0FGR8)
Extended synaptotagmin-2 (E-Syt2) (Chr2Syt)
Gene: ESYT2

Interactor 2: RTN3 (O95197)
Reticulon-3 (Homolog of ASY protein) (HAP) (Neuroendocrine-specific protein-like 2) (NSP-like protein 2) (Neuroendocrine-specific protein-like II) (NSP-like protein II) (NSPLII)
Gene: RTN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 921 Hs			1 1032
+	Hs
		48526 ESYT2_HUMAN (1-921): 0: 839: 100.00		RTN4_HUMAN (64-1030): 9.26e-60: 225: 21.16
+	Hs
		48199 ESYT2_HUMAN (1-921): 0: 839: 100.00		RTN2_HUMAN (620-1024): 7.71e-50: 187: 22.49
+	Hs
		307105 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		RTN3_HUMAN (1-1032): 0: 645: 100.00
+	At
		1341032 MCTP8_ARATH (533-921): 9.81e-32: 135: 16.46		RTNLH_ARATH (790-1030): 8.2e-66: 224: 18.73
+	Hs
		1311413 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		RTN4_HUMAN (64-1030): 9.26e-60: 225: 21.16
+	Hs
		258966 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		RTN2_HUMAN (620-1024): 7.71e-50: 187: 22.49
+	Hs
		1087788 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		RTN1_HUMAN (271-1028): 2.29e-45: 178: 22.73