HitPredict

Interactor 1: ESYT2 (A0FGR8)
Extended synaptotagmin-2 (E-Syt2) (Chr2Syt)
Gene: ESYT2

Interactor 2: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane and 1 others more... GO:0045296 - cadherin binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 921 Hs			1 654
+	Hs
		48244 ESYT2_HUMAN (1-921): 0: 839: 100.00		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		502276 SYT9_HUMAN (687-919): 6.25e-34: 138: 20.43		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		504666 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		502489 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		504873 MYOF_HUMAN (387-664): 4.34e-14: 79.1: 14.04		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		502623 MYOF_HUMAN (387-664): 4.34e-14: 79.1: 14.04		BIP_HUMAN (19-654): 0: 914: 100.00