HitPredict

Interactor 1: TPC2A (P0DI81)
Trafficking protein particle complex subunit 2 (Sedlin)
Gene: TRAPPC2

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0044325 - transmembrane transporter binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 245
+	Hs
		483303 TPC2B_HUMAN (1-140): 8.79e-67: 200: 100.00		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		483241 TPC2A_HUMAN (1-140): 8.79e-67: 200: 100.00		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		483301 TPC2B_HUMAN (1-140): 8.79e-67: 200: 100.00		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		483232 TPC2A_HUMAN (1-140): 8.79e-67: 200: 100.00		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		483288 TPC2B_HUMAN (1-140): 8.79e-67: 200: 100.00		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		483234 TPC2A_HUMAN (1-140): 8.79e-67: 200: 100.00		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		483290 TPC2B_HUMAN (1-140): 8.79e-67: 200: 100.00		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		483240 TPC2A_HUMAN (1-140): 8.79e-67: 200: 100.00		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		483300 TPC2B_HUMAN (1-140): 8.79e-67: 200: 100.00		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		483244 TPC2A_HUMAN (1-140): 8.79e-67: 200: 100.00		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49
+	Hs
		483306 TPC2B_HUMAN (1-140): 8.79e-67: 200: 100.00		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49