HitPredict

Interactor 1: ESYT2 (A0FGR8)
Extended synaptotagmin-2 (E-Syt2) (Chr2Syt)
Gene: ESYT2

Interactor 2: STX4 (Q12846)
Syntaxin-4 (Renal carcinoma antigen NY-REN-31)
Gene: STX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C2~SNARE, C2~Syntaxin
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 921 Hs			1 297
+	Hs
		48187 ESYT2_HUMAN (1-921): 0: 839: 100.00		STX7_HUMAN (31-291): 4.47e-50: 167: 23.95
+	Dm
		599152 SY65_DROME (607-919): 3.57e-30: 127: 16.14		STX1A_DROME (2-293): 8.97e-68: 214: 38.91
+	Hs
		1017772 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		STX4_HUMAN (1-297): 3e-70: 221: 100.00
+	Hs
		599551 SYT1_HUMAN (787-910): 3.15e-13: 74.7: 35.20		STX2_HUMAN (1-295): 4.47e-72: 225: 42.57
+	Rn
		600312 SYT1_RAT (787-910): 2.89e-13: 74.7: 35.20		STX1A_RAT (1-293): 1.02e-71: 224: 43.54
+	Hs
		699277 SYTL4_HUMAN (788-902): 3.42e-12: 72.4: 33.05		STX2_HUMAN (1-295): 4.47e-72: 225: 42.57
+	Hs
		599566 SYT1_HUMAN (787-910): 3.15e-13: 74.7: 35.20		STX4_HUMAN (1-297): 3e-70: 221: 100.00
+	Hs
		599575 SYT1_HUMAN (787-910): 3.15e-13: 74.7: 35.20		STX1A_HUMAN (1-293): 1.9e-70: 221: 43.20
+	Hs
		1083970 SYTL4_HUMAN (788-902): 3.42e-12: 72.4: 33.05		STX1A_HUMAN (1-293): 1.9e-70: 221: 43.20
+	Mm
		192842 SYT2_MOUSE (315-513): 8.25e-10: 64.1: 18.22		STX1A_MOUSE (1-293): 8.03e-72: 224: 43.54
+	Hs
		178751 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		STX7_HUMAN (31-291): 4.47e-50: 167: 23.95
+	Hs
		599569 SYT1_HUMAN (787-910): 3.15e-13: 74.7: 35.20		STX3_HUMAN (1-295): 6.64e-57: 186: 38.31
+	Hs
		1030179 SYTL4_HUMAN (788-902): 3.42e-12: 72.4: 33.05		STX3_HUMAN (1-295): 6.64e-57: 186: 38.31