HitPredict

Interactor 1: RBY1A (P0DJD3)
RNA-binding motif protein, Y chromosome, family 1 member A1 (RNA-binding motif protein 1) (RNA-binding motif protein 2) (Y chromosome RNA recognition motif 1) (hRBMY)
Gene: RBMY1A1

Interactor 2: CIRBP (Q14011)
Cold-inducible RNA-binding protein (A18 hnRNP) (Glycine-rich RNA-binding protein CIRP)
Gene: CIRBP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.740

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex GO:0048026 - positive regulation of mRNA splicing, via spliceosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 496 Hs			1 172
+	Hs
		1047862 RBY1F_HUMAN (1-496): 2.57e-65: 220: 99.19		CIRBP_HUMAN (1-172): 1.12e-39: 134: 100.00
+	Hs
		483437 RBY1A_HUMAN (1-496): 1.3e-65: 221: 100.00		RBM3_HUMAN (1-166): 4.5e-33: 116: 54.22
+	Hs
		958194 RBY1F_HUMAN (1-496): 2.57e-65: 220: 99.19		RBM3_HUMAN (1-166): 4.5e-33: 116: 54.22
+	Hs
		483431 RBY1A_HUMAN (1-496): 1.3e-65: 221: 100.00		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Hs
		62458 RBY1E_HUMAN (1-496): 1.96e-65: 221: 99.60		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Hs
		745179 RBY1F_HUMAN (1-496): 2.57e-65: 220: 99.19		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Hs
		483430 RBY1A_HUMAN (1-496): 1.3e-65: 221: 100.00		RBY1A_HUMAN (2-118): 7.64e-16: 75.9: 51.28
+	Hs
		483440 RBY1A_HUMAN (1-496): 1.3e-65: 221: 100.00		RBY1F_HUMAN (2-118): 1.22e-14: 72.4: 49.57
+	Hs
		62459 RBY1E_HUMAN (1-496): 1.96e-65: 221: 99.60		RBY1F_HUMAN (2-118): 1.22e-14: 72.4: 49.57
+	Hs
		925044 RBY1F_HUMAN (1-496): 2.57e-65: 220: 99.19		TRA2B_HUMAN (8-132): 2.95e-15: 73.2: 46.40
+	Hs
		1073368 RBY1F_HUMAN (1-496): 2.57e-65: 220: 99.19		RBY1F_HUMAN (2-118): 1.22e-14: 72.4: 49.57
+	Hs
		745164 SAFB2_HUMAN (6-489): 1.22e-39: 155: 13.32		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Hs
		745180 SAFB1_HUMAN (7-489): 4.16e-39: 153: 16.02		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Hs
		516744 PPIE_HUMAN (10-95): 3.23e-31: 124: 39.08		PABP1_HUMAN (7-162): 4.32e-26: 105: 18.59
+	Hs
		925150 PPIE_HUMAN (10-95): 3.23e-31: 124: 39.08		TRA2B_HUMAN (8-132): 2.95e-15: 73.2: 46.40
+	Hs
		852206 PPIE_HUMAN (10-95): 3.23e-31: 124: 39.08		ROA3_HUMAN (7-92): 2.98e-14: 70.9: 43.02
+	At
		98366 F4JVB9_ARATH (4-69): 3.19e-27: 107: 32.84		RBG7_ARATH (5-82): 3.45e-15: 71.2: 48.72