Interactor 1: AP3A (P0DTC3)
ORF3a protein (ORF3a) (Accessory protein 3a) (Protein 3a) (Protein U274) (Protein X1)
Gene: 3a

Interactor 2: AP3A (P0DTC3)
ORF3a protein (ORF3a) (Accessory protein 3a) (Protein 3a) (Protein U274) (Protein X1)
Gene: 3a

Species: Severe acute respiratory syndrome coronavirus 2

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 33845483, 34709727, 36695574, 34672954, 34158638, 888800000946, 34041264, 32587976
Identification Methods affinity chromatography technology, proximity labelling technology, x-ray crystallography, pull down, fluorescent resonance energy transfer, 3D electron microscopy
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains bCoV_viroporin~bCoV_viroporin
Common GO terms GO:0005216 - monoatomic ion channel activity
GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0005891 - voltage-gated calcium channel complex
GO:0008076 - voltage-gated potassium channel complex
and 11 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 275
Sa

1 275
+ Sa

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024