HitPredict

Interactor 1: ESYT2 (A0FGR8)
Extended synaptotagmin-2 (E-Syt2) (Chr2Syt)
Gene: ESYT2

Interactor 2: ESYT1 (Q9BSJ8)
Extended synaptotagmin-1 (E-Syt1) (Membrane-bound C2 domain-containing protein)
Gene: ESYT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.945

The method score is based on:

Property Details
Experiments 22119785, 35271311, 37931956, 37071682, 27065097, 23791178
Identification Methods affinity chromatography technology, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C2~C2, C2~SMP_LBD, SMP_LBD~SMP_LBD
Common GO terms GO:0005509 - calcium ion binding
GO:0005544 - calcium-dependent phospholipid binding
GO:0005789 - endoplasmic reticulum membrane
GO:0008429 - phosphatidylethanolamine binding
GO:0016020 - membrane
and 4 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 921
Hs

1 1104
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Last updated: 15 Jul 2024