Protein: ACHA3
Neuronal acetylcholine receptor subunit alpha-3

Gene: ACHA3, CHRNA3
Organism: Homo sapiens
Interactions: 52
UniProt ID: P32297

Gene Ontology (top 5):
GO:0005730 - nucleolus
GO:0005783 - endoplasmic reticulum
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

607908

ACHB2
Neuronal acetylcholine receptor subunit beta-2

3

18

Small-scale

0.839

High

733690

5HT3A
5-hydroxytryptamine receptor 3A

2

18

High-throughput

0.811

High

733691

GLRB
Glycine receptor subunit beta

2

17

High-throughput

0.811

High

733710

LEMD2
LEM domain-containing protein 2

3

7

High-throughput

0.662

High

253815

TPST2
Protein-tyrosine sulfotransferase 2

2

3

High-throughput

0.628

High

269996

XYLK
Glycosaminoglycan xylosylkinase

2

1

High-throughput

0.628

High

733692

MFAP3
Microfibril-associated glycoprotein 3

2

4

High-throughput

0.628

High

733696

ITPR2
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2

2

1

High-throughput

0.628

High

733697

ITPR3
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3

2

1

High-throughput

0.628

High

733702

TMPPE
Transmembrane protein with metallophosphoesterase domain

2

2

High-throughput

0.628

High

733704

TM219
Insulin-like growth factor-binding protein 3 receptor

2

1

High-throughput

0.628

High

733706

MIB1
E3 ubiquitin-protein ligase MIB1

2

1

High-throughput

0.628

High

733709

GHDC
GH3 domain-containing protein

2

3

High-throughput

0.628

High

733712

EDA
Ectodysplasin-A

2

4

High-throughput

0.628

High

733714

ASTRA
Protein Aster-A

2

5

High-throughput

0.628

High

733716

APOL2
Apolipoprotein L2

2

2

High-throughput

0.628

High

733718

GL8D2
Glycosyltransferase 8 domain-containing protein 2

2

2

High-throughput

0.628

High

733720

ENTP7
Ectonucleoside triphosphate diphosphohydrolase 7

2

6

High-throughput

0.628

High

733721

CNNM1
Metal transporter CNNM1

2

3

High-throughput

0.628

High

733724

DSE
Dermatan-sulfate epimerase

2

1

High-throughput

0.628

High

733713

TM143
Transmembrane protein 143

2

0

High-throughput

0.602

High

539694

ACHB
Acetylcholine receptor subunit beta

1

18

High-throughput

0.575

High

720404

ACHA5
Neuronal acetylcholine receptor subunit alpha-5

1

18

Small-scale

0.575

High

49438

TM223
Transmembrane protein 223

2

1

High-throughput

0.574

High

733700

DIK1A
Divergent protein kinase domain 1A

2

2

High-throughput

0.574

High

733715

FACR2
Fatty acyl-CoA reductase 2

2

2

High-throughput

0.574

High

733719

TM231
Transmembrane protein 231

2

1

High-throughput

0.574

High

516628

LYNX1
Ly-6/neurotoxin-like protein 1

2

6

Small-scale

0.552

High

170676

CLGN
Calmegin

1

7

High-throughput

0.536

High

733701

KLC3
Kinesin light chain 3

1

2

High-throughput

0.536

High

733708

PLD6
Mitochondrial cardiolipin hydrolase

1

2

High-throughput

0.536

High

733723

EXTL2
Exostosin-like 2

1

5

High-throughput

0.536

High

733725

SIA10
Type 2 lactosamine alpha-2,3-sialyltransferase

1

7

High-throughput

0.536

High

733695

DOC2B
Double C2-like domain-containing protein beta

1

0

High-throughput

0.513

High

733707

C1QL4
Complement C1q-like protein 4

1

6

High-throughput

0.489

High

733699

RBBP7
Histone-binding protein RBBP7

1

1

High-throughput

0.479

High

733722

P2RX2
P2X purinoceptor 2

1

4

Small-scale

0.479

High

254842

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

1

High-throughput

0.445

High

277001

ENTP6
Ectonucleoside triphosphate diphosphohydrolase 6

1

6

High-throughput

0.445

High

582550

PPAP
Prostatic acid phosphatase

1

1

High-throughput

0.445

High

638124

AOFA
Amine oxidase [flavin-containing] A

1

1

High-throughput

0.445

High

733698

MFS10
Major facilitator superfamily domain-containing protein 10

1

1

High-throughput

0.445

High

733705

LYPD6
Ly6/PLAUR domain-containing protein 6

1

6

Small-scale

0.445

High

733717

SEM4C
Semaphorin-4C

1

2

High-throughput

0.445

High

733694

SBP1
Methanethiol oxidase

1

0

High-throughput

0.426

High

733703

DSG4
Desmoglein-4

1

0

High-throughput

0.426

High

733711

LRC15
Leucine-rich repeat-containing protein 15

1

0

High-throughput

0.426

High

407839

SEMG1
Semenogelin-1

1

1

High-throughput

0.407

High

733693

SEMG2
Semenogelin-2

1

1

High-throughput

0.407

High

49776

CLRN2
Clarin-2

1

0

High-throughput

0.279

Low

326663

DUS14
Dual specificity protein phosphatase 14

1

0

High-throughput

0.232

Low

733689

SPB5
Serpin B5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025