Interactor 1: GLI3 (P10071)
Transcriptional activator GLI3 (GLI3 form of 190 kDa) (GLI3-190) (GLI3 full-length protein) (GLI3FL) [Cleaved into: Transcriptional repressor GLI3R (GLI3 C-terminally truncated form) (GLI3 form of 83 kDa) (GLI3-83)]
Gene: GLI3

Interactor 2: PGBM (P98160)
Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) (Perlecan) (PLC) [Cleaved into: Endorepellin; LG3 peptide]
Gene: HSPG2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.500

The method score is based on:

Property Details
Experiments 35140242
Identification Methods affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0007224 - smoothened signaling pathway
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1580
Hs

1 4391
+ Dm
+ Dm
+ Hs

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Last updated: 15 Jul 2024